Most, if not all, cell types and tissues display several aspects of polarization. In addition to
the ubiquitous epithelial cell polarity along the apical-basolateral axis, many epithelial …

Primary (nonmotile) cilia are currently enjoying a renaissance in light of novel ascribed
functions ranging from mechanosensory to signal transduction. Their importance for key …

The planar cell polarity (PCP) signaling system governs many aspects of polarized cell
behavior. Here, we use an in vivo model of vertebrate mucociliary epithelial development to …

Neural tube defects (NTDs) are very frequent congenital abnormalities in humans. Recently,
we have documented independent association of Vangl1 and Vangl2 gene mutations with …

Fetuses with neural tube defects (NTDs) may suffer from associated syndromes and
disorders. This article provides a comprehensive review of the syndromes and disorders …

Fetuses with neural tube defects (NTDs) maybe associated with syndromes, disorders, and
maternal risk factors. This article provides a comprehensive review of syndromes, disorders …

Neural tube defects (NTDs) are among the most common structural birth defects observed in
humans. Mouse models provide an excellent experimental system to study the underlying …

Анализ данных аутопсий 22 новорожденных детей показал, что ведущим
изолированным пороком была врожденная гидроцефалия (40, 0±16, 3%). Одинаково …

神经管畸形的发生是由遗传因素与环境因素共同作用产生的. 平面细胞极性途径(planar cell
polarity, PCP) 对脊椎动物神经胚形成非常重要. 该途径基因的任何突变都可能导致神经管不能 …

This study reports the effects of retinoic acid on the spatiotemporal expressions of Vangl1
and Vangl2 in mouse fetuses. A single dose of 120 mg/kg body weight of all-trans-retinoic …