Intimate Molecular Interactions of P. falciparum Merozoite Proteins Involved in Invasion of Red Blood Cells and Their Implications for Vaccine Design

LE Rodriguez, H Curtidor, M Urquiza… - Chemical …, 2008 - ACS Publications
Intimate Molecular Interactions of P. falciparum Merozoite Proteins Involved in Invasion of Red
Blood Cells and Their Implications for Vaccine Design | Chemical Reviews ACS ACS …

Breadth and Magnitude of Antibody Responses to Multiple Plasmodium falciparum Merozoite Antigens Are Associated with Protection from Clinical Malaria

FHA Osier, G Fegan, SD Polley, L Murungi… - Infection and …, 2008 - Am Soc Microbiol
Individuals living in areas where malaria is endemic are repeatedly exposed to many
different malaria parasite antigens. Studies on naturally acquired antibody-mediated …

Humoral Responses to Plasmodium falciparum Blood-Stage Antigens and Association with Incidence of Clinical Malaria in Children Living in an Area of Seasonal …

I Nebie, A Diarra, A Ouedraogo, I Soulama… - Infection and …, 2008 - Am Soc Microbiol
There is longstanding evidence that immunoglobulin G (IgG) has a role in protection against
clinical malaria, and human antibodies of the cytophilic subclasses are thought to be …

Cohort study of the association of antibody levels to AMA1, MSP119, MSP3 and GLURP with protection from clinical malaria in Ghanaian children

D Dodoo, A Aikins, KA Kusi, H Lamptey, E Remarque… - Malaria journal, 2008 - Springer
Background Antigen-specific antibody-mediated immune responses play an important role
in natural protection against clinical malaria, but conflicting estimates of this association …

Evaluation of immunoglobulin purification methods and their impact on quality and yield of antigen-specific antibodies

ES Bergmann-Leitner, RM Mease, EH Duncan, F Khan… - Malaria journal, 2008 - Springer
Background Antibodies are the main effectors against malaria blood-stage parasites.
Evaluation of functional activities in immune sera from Phase 2a/b vaccine trials may provide …

Antibodies to Plasmodium falciparum and Plasmodium vivax Merozoite Surface Protein 5 in Indonesia: Species-Specific and Cross-Reactive Responses

T Woodberry, G Minigo, KA Piera… - The Journal of …, 2008 - academic.oup.com
Background. Merozoite surface protein (MSP) 5 is a candidate antigen for a malaria vaccine.
In cross-sectional and longitudinal studies, we measured MSP5 antibody responses in …

Do antibody responses to malaria vaccine candidates influenced by the level of malaria transmission protect from malaria?

I Nebie, AB Tiono, DA Diallo… - Tropical medicine & …, 2008 - Wiley Online Library
Objectives To examine whether the humoural response to malaria vaccine candidate
antigens, Plasmodium falciparum [circumsporozoite repetitive sequence (NANP) 5 GLURP …

Longitudinal analyses of immune responses to Plasmodium falciparum derived peptides corresponding to novel blood stage antigens in coastal Kenya

GW Agak, P Bejon, G Fegan, N Gicheru, V Villard… - Vaccine, 2008 - Elsevier
We have recently described 95 predicted α-helical coiled-coil peptides derived from putative
Plasmodium falciparum erythrocytic stage proteins. Seventy peptides recognized with the …

Various carrier system (s)-mediated genetic vaccination strategies against malaria

RK Tyagi, PK Sharma, SP Vyas, A Mehta - Expert Review of Vaccines, 2008 - go.gale.com
Although immune mechanism identification, antigenic target recognition for immune
mechanisms and development of vaccine-delivery systems for the induction of the desired …

Linkage Group Selection to Investigate Genetic Determinants of Complex Traits of Malaria Parasites

S Pattaradilokrat - 2008 - era.ed.ac.uk
Malaria parasites of the species infecting humans and animal hosts exhibit genetic and
phenotypic diversity. Some of this diversity, including the responses to anti-malarial drugs …