Transglutaminases in vascular biology: relevance for vascular remodeling and atherosclerosis

ENTP Bakker, A Pistea, E VanBavel - Journal of vascular research, 2008 - karger.com
The transglutaminase (Tgase) family consists of nine known members of whom at least three
are expressed in the vascular system: type 1 Tgase, type 2 Tgase and factor XIII. The cross …

Simvastatin: two decades in a circle

GD Kolovou, I Vasiliadis… - Cardiovascular …, 2008 - Wiley Online Library
Simvastatin is an agent of the 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase inhibitor
group of drugs. It is administrated orally once a day in doses of 5–80 mg. Although its main …

Simvastatin abates development of renal fibrosis in experimental renovascular disease

AR Chade, XY Zhu, JP Grande, JD Krier… - Journal of …, 2008 - journals.lww.com
Methods Renal hemodynamics, function, and endothelial function were quantified in vivo in
pigs after 12 weeks of combined hypercholesterolemia+ renal artery stenosis without (n= 8) …

Disparate effects of simvastatin on angiogenesis during hypoxia and inflammation

XY Zhu, E Daghini, AR Chade, R Lavi, C Napoli… - Life sciences, 2008 - Elsevier
AIMS: Studies have shown that some of statin's pleiotropic effects were achieved by either
promotion or inhibition of angiogenesis, depending on the underlying disease. This study …

Pleiotropic effects of statins may improve outcomes in atherosclerotic renovascular disease

VS Silva, LC Martin, RJS Franco… - American journal of …, 2008 - academic.oup.com
Background Atherosclerotic renovascular disease (ARD) coexists with arterial obstructive
disease in the coronary, cerebral, and peripheral arteries that may remain underdiagnosed …

Ишемическая болезнь почек: Клиническая картина, патогенез, тактика ведения

ВВ Фомин - 2008 - static.freereferats.ru
Внедрение в клиническую практику высокоинформативных методов обследования
способствовало детальному уточнению особенностей клинической картины и течения …

Atheromatous renovascular disease: overview and challenges

C Chrysochou, PA Kalra - Journal of Renal Care, 2008 - Wiley Online Library
Atheromatous renovascular disease (ARVD) is a common and challenging disease. It is
increasingly associated with chronic kidney disease (CKD) and end‐stage renal disease …

Inflammation in renal atherosclerotic disease

SM Udani, RS Dieter - Expert Review of Cardiovascular Therapy, 2008 - Taylor & Francis
The study of renal atherosclerotic disease has conventionally focused on the diagnosis and
management of renal artery stenosis. With the increased understanding of atherosclerosis …

Statin therapy in ARAS: beyond cholesterol lowering

P Meier - American journal of hypertension, 2008 - academic.oup.com
Atherosclerotic renal artery stenosis (ARAS) accounts for over a third of all cases of end-
stage kidney disease. 1 Furthermore, ARAS represents a common manifestation of …

Simvastatin, an inhibitor of epithelial-to-mesenchymal transition in experimental atherosclerotic renovascular disease?

A Agrotis - Journal of Hypertension, 2008 - journals.lww.com
Renal artery stenosis (RAS) is defined as narrowing of the renal artery lumen. It has been
estimated that atherosclerosis, usually involving the ostium and proximal third of the main …