Mechanical stresses are ever present in the cellular environment, whether through external
forces that are applied to tissues or endogenous forces that are generated within the active …

The cytoskeleton (CSK) of the adherent living cell is arguably the most complex form of soft
matter that exists in nature. It is constituted by hundreds of different proteins that interact with …

As the most rigid cytoskeletal filaments, microtubules bear compressive forces in living cells,
balancing the tensile forces within the cytoskeleton to maintain the cell shape. It is often …

Dynamic organization of the cell interior, which is crucial for cell function, largely depends on
the microtubule cytoskeleton. Microtubules move and position organelles by pushing …

Vascular smooth muscle cells (VSMC) situated in the tunica media of veins and arteries are
central to maintaining conduit integrity in the face of mechanical forces inherent within the …

The effects of actin filaments (AFs) and microtubules (MTs) on quasi-in situ tensile properties
and intracellular force balance were studied in cultured rat aortic smooth muscle cells …

The cytoskeleton provides the mechanical scaffold and maintains the integrity of cells. It is
usually believed that one type of cytoskeleton biopolymer, microtubules, bears compressive …

Actin stress fibers (SFs) enable cells to sense and respond to mechanical stimuli and affect
adhesion, motility and apoptosis. We and others have demonstrated that cultured human …

The biomechanical behavior of an adherent cell is intimately dependent on its cytoskeleton
structure. Several models have been proposed to study this structure taking into account its …

The role of actin filaments and microtubules in 3D cell morphology was investigated using
confocal laser scanning microscopy and image analysis based on a regiongrowing method …