Molecular mechanisms and consequences of angiogenesis in osteoarthritis are slowly
being elucidated. Studies, both in humans and animal models, support the notion that …

Although adult human cartilage is physiologically avascular tissue, angiogenesis can be
observed during the process of endochondral bone development. Inflammation in articular …

Introduction Cannabis-based medicines have a number of therapeutic indications, including
anti-inflammatory and analgesic effects. The endocannabinoid receptor system, including …

Osteoarthritis is an inflammatory disease of load-bearing synovial joints that is currently
treated with drugs that exhibit numerous side effects and are only temporarily effective on …

Objective: To quantify inflammatory changes in synovial membranes from orthopaedic “non-
inflammatory” arthropathies (Orth. A). Methods: Synovial membranes from patients with …

Osteoarthritis and rheumatoid arthritis pannus have similar qualitative metabolic
characteristics and pro-inflammatory cytokine Page 1 Clinical and Experimental …

The traditional view of OA is that it is primarily a disease of articular cartilage that results, by
altering the biomechanics of the joint, in secondary changes to the subchondral bone and …

OBJECTIVE: We have previously described angiogenesis at the osteochondral junction and
in synovium of knees from patients with osteoarthritis (OA), but little is known about how …

Objective. IA therapy with hyaluronan (HA) is reported to provide symptomatic relief and
disease modification in OA. This study assessed the pathological changes in the synovium …

Objective Synovial mesenchymal stem cells (MSCs) are an attractive cell source for cartilage
regeneration because of their high chondrogenic ability. In this study, we examined the …