Human cytomegalovirus infects human populations at a high frequency worldwide. During
the long coevolution of virus and host, a fine balance has developed between viral immune …

Background Human Ig-like transcript 4 (ILT-4) is a member of the inhibitory receptor family
for immune function. Little is known about the expression levels of ILT-4 in tumor cells …

Recent advances support an important role for NK cells in determining immune responses
beyond their cytolytic functions, which is supported by their capacity to secrete several …

BACKGROUND In the early stages of human placentation, the decidua is invaded by fetal
extravillous trophoblast (EVT) cells. Interactions between EVT cells and local decidual …

Candidate trigger antigens for alloreactive responses have been appearing continuously in
the organ transplant scenario. Major histocompatibility complex class I–related chain A …

Natural killer (NK) cells are an important component of the innate immune response against
intracellular pathogens and also play a role in the tissue inflammation associated with …

The major task for the immune system is to recognize and eliminate non-self molecules and
pathogens. Deficiencies in any part of the immune system result in a higher risk of infections …

Inhibitory MHC class I receptors are mainly expressed on NK cells. NK cells bear various
kinds of inhibitory MHC class I receptors, Killer cell immunoglobulin (Ig)-like receptors …

Natural killer (NK) cells are innate immune cells that contribute to defense against infected
and transformed cells by target cell killing and cytokine release. In addition, data suggest …

Herpesviruses are ubiquitous pathogens which after an often asymptomatic infection
establish lifelong latency in the host. Control of the viral infection depends on both innate …