Objective To determine the efficacy of statin treatment on risk of coronary heart disease in
patients with familial hypercholesterolaemia. Design Cohort study with a mean follow-up of …

The genetic basis of coronary artery disease (CAD) is complex, and the fact that an
alarmingly high proportion of reported associations between genetic variants and CAD are …

Background The vast majority of genetic risk factors for complex diseases have, taken
individually, a small effect on the end phenotype. Population-based association studies …

“Personalized medicine” is a new buzz phrase, based initially on pharmacogenetics and
now exploding as genome-wide association studies are undertaken. However, it still …

Objective—The purpose of this study was to assess femoral atherosclerosis by ultrasound in
patients with molecularly defined heterozygous familial hypercholesterolemia (FH) in …

Common multigene disorders account for 80% of deaths in the world and all have significant
genetic predisposition. Coronary artery disease and myocardial infarction (MI) account for …

Development work toward an enabling synthesis of preparative scale batches of an
imidazole-based HMG-CoA reductase inhibitor is described. The desired target was …

Özet Yaşlanma, multifaktoriyel bir olaydır ve genetik ve çevresel faktörlerden tarzından
etkilenir. Zamanla sistemlerin bozulması sürecidir ve biyokimyasal ve morfolojik düzeyde …

Yüksek lisans eğitimim süresince deneysel çalışmalarımı yapabilmem için gerekli olan tüm
laboratuvar olanaklarının ve tezim için gerekli hasta örneklerinin toplanmasındaki …

Τα καρδιαγγειακά νοσήματα τις τελευταίες δεκαετίες αποτελούν μάστιγα στις βιομηχανικά
ανεπτυγμένες χώρες και τείνουν να μετατραπούν σε πανδημία για τον πλανήτη. Βήματα προς …