Glutamate's role as a neurotransmitter at synapses has been known for 40 years, but
glutamate has since been shown to regulate neurogenesis, neurite outgrowth …

The neurotrophins are a family of closely related proteins that were first identified as survival
factors for sympathetic and sensory neurons, and have since been shown to control a …

Amyotrophic lateral sclerosis (ALS) is a late-onset progressive degeneration of motor
neurons occurring both as a sporadic and a familial disease. The etiology of ALS remains …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease where motor neurons
within the brain and spinal cord are lost, leading to paralysis and death. Certain growth …

Background: Besides its role in neuronal growth and differentiation, brain-derived
neurotrophic factor (BDNF) has been implicated in the control of peristalsis where it serves …

Physical exercise exerts a wide range of benefits on an organism's overall health and well-
being. Exercise contributes positively toward an individual's healthy weight, muscle strength …

Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family of
neurotrophic factors. BDNF has long been recognized to have potential for the treatment of a …

Progression of disease and effectiveness of therapy in patients with amyotrophic lateral
sclerosis (ALS) are determined by both questionnaire‐and examination‐based measures …

Several therapies have shown promise in preclinical models of motor neuron disease.
Several of these treatment approaches, however, failed in human studies. In moving forward …

Amyotrophic lateral sclerosis (ALS) is a devastating condition characterized by progressive
muscle wasting, inanition, respiratory failure, and death within approximately 2 to 5 years of …