Molecular mechanisms of anti-inflammatory activity mediated by flavonoids

A Gomes, E Fernandes, JLFC Lima… - Current medicinal …, 2008 - ingentaconnect.com
Flavonoids (or bioflavonoids) are naturally occurring compounds, ubiquitous in all vascular
plants. These compounds have been considered to possess anti-inflammatory properties …

Suppressive effects of flavonoid fisetin on lipopolysaccharide-induced microglial activation and neurotoxicity

LT Zheng, J Ock, BM Kwon, K Suk - International immunopharmacology, 2008 - Elsevier
Microglia are innate immune cells in the central nervous system. Activation of microglia
plays an important role in the processes of several neurodegenerative diseases including …

Validation of a new method using the reactivity of electrogenerated superoxide radical in the antioxidant capacity determination of flavonoids

C Le Bourvellec, D Hauchard, A Darchen, JL Burgot… - Talanta, 2008 - Elsevier
This article lays out a new method to measure the antioxidant capacity of some flavonoids.
The methodology developed is based on the kinetics of the reaction of the antioxidant …

Radical-scavenging abilities and antioxidant properties of theaflavins and their gallate esters in H2O2-mediated oxidative damage system in the HPF-1 cells

Z Yang, G Jie, F Dong, Y Xu, N Watanabe, Y Tu - Toxicology in Vitro, 2008 - Elsevier
The antioxidant properties of theaflavins and their gallate esters, namely theaflavin (TF1),
theaflavin-3 (3′)-gallate (TF2) and theaflavin-3, 3′-digallate (TF3) were investigated by …

Protective capacities of certain spices against peroxynitrite-mediated biomolecular damage

SC Ho, TH Tsai, PJ Tsai, CC Lin - Food and Chemical Toxicology, 2008 - Elsevier
Peroxynitrite, a potent cytotoxic agent, can damage a variety of biomolecules such as
proteins, lipids, and DNA, and is considered as one of the major pathological causes of …

Antiproliferative, Antioxidant, and Antimutagenic Activities of Flavonoid-Enriched Extracts from (Tunisian) Rhamnus alaternus L.: Combination with the Phytochemical …

R Ben Ammar, S Kilani, I Bouhlel, L Ezzi… - Drug and Chemical …, 2008 - Taylor & Francis
A pronounced antiproliferative effect on human leukemia K562 cells was shown with
flavonoid-enriched extracts from Rhamnus alaternus roots and leaves, with, respectively …

The changes of antioxidant defense system caused by quercetin administration do not lead to DNA damage and apoptosis in the spleen and bone marrow cells of rats

MA Papiez, A Cierniak, W Krzysciak, M Bzowska… - Food and Chemical …, 2008 - Elsevier
Quercetin may have the opposite effect, namely anti-as well as pro-oxidant. The aim of this
study was to assess the results of quercetin anti-and/or pro-oxidant activity in the bone …

Quercetin prevents necrotic cell death induced by co-exposure to benzo (a) pyrene and UVA radiation

HD Woo, BM Kim, YJ Kim, YJ Lee, SJ Kang, YH Cho… - Toxicology in Vitro, 2008 - Elsevier
The phototoxicity of low-energy ultraviolet radiation, such as UVA, can be enhanced by the
presence of photosensitizing agents. Hence, co-exposure of cells to benzo [a] pyrene (BaP) …

Antimutagenic, antigenotoxic and antioxidant activities of Acacia salicina extracts (ASE) and modulation of cell gene expression by H2O2 and ASE treatment

I Bouhlel, K Valenti, S Kilani, I Skandrani, MB Sghaier… - Toxicology in Vitro, 2008 - Elsevier
The total oligomers flavonoids (TOF), chloroform, petroleum ether and aqueous extracts from
Acacia salicina, were investigated for the antioxidative, cytotoxic, antimutagenic and …

[PDF][PDF] Protective effect of flavanoidal fraction of Indigofera tinctoria on benzo (a) pyrene induced lung carcinogenicity in Swiss albino mice

K Ravichandran, R Ravichandran - Int. J. Cancer Res, 2008 - academia.edu
The chemopreventive effect ofthe flavanoidal fraction of hadigofera tinctoria were evaluated
in Swiss albino mice using lő week medium ten model of benzo (a) pyrene (BP)-induced …