Brain renin angiotensin in disease

MI Phillips, EM De Oliveira - Journal of molecular medicine, 2008 - Springer
A brain renin angiotensin system (RAS) and its role in cardiovascular control and fluid
homeostasis was at first controversial. This was because a circulating kidney-derived renin …

[HTML][HTML] Role of angiotensin II AT1 receptor activation in cardiovascular diseases

S Billet, F Aguilar, C Baudry, E Clauser - Kidney international, 2008 - Elsevier
Numerous clinical studies and experimental investigations using cell culture and animal
models suggest that angiotensin II (AngII) via AT 1 receptor activation might induce …

[HTML][HTML] Cardiovascular activity

HG Vogel - Drug Discovery and Evaluation, 2008 - ncbi.nlm.nih.gov
PURPOSE AND RATIONALE α1-adrenoceptors are widely distributed and are activated
either by norepinephrine released from sympathetic nerve terminals or by epinephrine …

A growing chain of evidence linking genetic variation in angiotensinogen with essential hypertension: focus on “A haplotype of human angiotensinogen gene …

CD Sigmund - American Journal of Physiology-Regulatory …, 2008 - journals.physiology.org
THE PREVALENCE OF HYPERTENSION across the globe continues to rise despite
advances in treatment and an ever-growing battery of antihypertensive drugs. Untreated …

Associação dos polimorfismos dos genes ECA e AT1R com a hipertensão arterial ea resposta à terapêutica anti-hipertensiva em idosas brasileiras

CF Moraes - 2008 - bdtd.ucb.br
Objetivo: Sabendo-se que hipertensão arterial sistêmica (HAS) é condição prevalente entre
idosos e que o sistema renina angiotensina (SRA) exerce função primordial na regulação …

Antisense Therapeutics for Hypertension

MI Phillips, B Kimura - Antisense Therapeutics, 2008 - Springer
Antisense therapeutics can be applied to hypertension. Hypertension is a widespread
disease, yet in spite of several excellent drugs for the treatment of hypertension, the number …