Altered regulation of tyrosine kinase receptors (RTKs) is frequent in solid tumours and it is
often associated with the acquisition of an aggressive phenotype. Thus, therapies targeting …

The close genotype-phenotype relationship that characterizes thyroid oncology stimulated
the authors to address this article by using a mixed, genetic and phenotypic approach. As …

Context: Familial nonmedullary thyroid carcinoma (FNMTC) accounts for approximately 5%
of all thyroid tumors. Genetic mapping studies have identified four different chromosomal …

Rac1, a Rho GTPase, modulates diverse cellular processes and is hyperactive in some
cancers. Estrogen receptor-alpha (ERα) in concert with intracellular signaling pathways …

The peroxisome proliferator-activated receptor-g (PPARg) is a member of the nuclear
hormone receptor superfamily. Ligand activation of PPARg is associated with differentiation …

Thyroid carcinoma cells often do not express thyroid-specific genes including sodium iodide
symporter (NIS), thyroperoxidase (TPO), thyroglobulin (TG), and thyrotropin-stimulating …

Anaplastic thyroid carcinoma is the most aggressive type of thyroid malignancies.
Previously, we demonstrated that tumorigenicity of anaplastic thyroid carcinoma cell line …

―――Abstract―――――――――――――――――――――――――――――――――――
―――――We report two rare cases of concurrent papillary thyroid carcinoma and follicular …

Thyroid cancer is the commonest endocrine malignancy. Several of the initiating genetic
events in thyroid tumorigenesis have been identified, although the exact molecular …