Click chemistry: A powerful tool to create polymer‐based macromolecular chimeras

B Le Droumaguet, K Velonia - Macromolecular Rapid …, 2008 - Wiley Online Library
The combination of polymeric with biological materials, to create biohybrid macromolecules
that merge the properties of both the natural and synthetic components, is a flourishing area …

Optimization of conditions for galactooligosaccharide synthesis during lactose hydrolysis by β-galactosidase from Kluyveromyces lactis (Lactozym 3000 L HP G)

C Martínez-Villaluenga, A Cardelle-Cobas, N Corzo… - Food Chemistry, 2008 - Elsevier
A study on optimisation of the conditions for galactooligosaccharide (GOS) formation during
lactose hydrolysis, produced by Lactozym 3000 L HP G, was carried out. The synthesis was …

Carbohydrate microarrays as powerful tools in studies of carbohydrate-mediated biological processes

S Park, MR Lee, I Shin - Chemical communications, 2008 - pubs.rsc.org
Carbohydrate microarrays have become very powerful tools to elucidate the molecular basis
of carbohydrate-recognition events in a high-throughput manner. This microarray technology …

On-virus construction of polyvalent glycan ligands for cell-surface receptors

E Kaltgrad, MK O'Reilly, L Liao, S Han… - Journal of the …, 2008 - ACS Publications
Glycans arrayed on the exterior of virus particles were used as substrates for
glycosyltransferase reactions to build di-and trisaccharides from the virus surface. The …

Stereoselective direct glycosylation with anomeric hydroxy sugars by activation with phthalic anhydride and trifluoromethanesulfonic anhydride involving glycosyl …

KS Kim, DB Fulse, JY Baek, BY Lee… - Journal of the American …, 2008 - ACS Publications
An efficient direct one-pot glycosylation method with anomeric hydroxy sugars as glycosyl
donors employing phthalic anhydride and triflic anhydride as activating agents has been …

Regioselective one-pot protection of glucose

CC Wang, SS Kulkarni, JC Lee, SY Luo, SC Hung - Nature Protocols, 2008 - nature.com
Detailed protocols for the regioselective protection of individual hydroxyls in
monosaccharide units are described here. This expedient methodology incorporates up to …

Oligomannan synthesis using ionic liquid supported glycosylation

AK Pathak, CK Yerneni, Z Young, V Pathak - Organic letters, 2008 - ACS Publications
The synthesis of complex oligosaccharides has been a challenge for researchers. Herein,
we describe a strategy for the synthesis of an activated oligomannan 1 that employs ionic …

A universal screening assay for glycosynthases: directed evolution of glycosynthase XynB2 (E335G) suggests a general path to enhance activity

A Ben-David, G Shoham, Y Shoham - Chemistry & biology, 2008 - cell.com
Glycosynthases are catalytic mutants of mainly retaining glycoside hydrolases that catalyze
the synthesis of oligosaccharides from their corresponding glycosyl-fluoride donors and …

Phenylenediamine catalysis of “click glycosylations” in water: practical and direct access to unprotected neoglycoconjugates

A Baron, Y Blériot, M Sollogoub… - Organic & Biomolecular …, 2008 - pubs.rsc.org
Phenylenediamine catalysis of “click glycosylations” in water: practical and direct access to
unprotected neoglycoconjugates - Organic & Biomolecular Chemistry (RSC Publishing) DOI:10.1039/B805528A …

Characterization of Helicobacter pylori α1,2‐Fucosyltransferase for Enzymatic Synthesis of Tumor‐Associated Antigens

DB Stein, YN Lin, CH Lin - Advanced Synthesis & Catalysis, 2008 - Wiley Online Library
Abstract The α1, 2‐fucosyltransferase (α1, 2‐FucT) from Helicobacter pylori catalyzes the
fucosylation of acceptor oligosaccharides at the C2‐OH of terminal Galβ units. The enzyme …