Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease

GP Anderson - The Lancet, 2008 - thelancet.com
Clinical asthma is very widely assumed to be the net result of excessive inflammation driven
by aberrant T-helper-2 (Th2) immunity that leads to inflamed, remodelled airways and then …

[HTML][HTML] Lipid droplets: FSP27 knockout enhances their sizzle

V Puri, MP Czech - The Journal of clinical investigation, 2008 - Am Soc Clin Investig
Fat-specific protein of 27 kDa (FSP27) is a highly expressed adipocyte protein that promotes
triglyceride accumulation within lipid droplets. In this issue of the JCI, Nishino et al. show that …

[HTML][HTML] It takes two to tango: cigarette smoke partners with viruses to promote emphysema

RM Tuder, JH Yun - The Journal of clinical investigation, 2008 - Am Soc Clin Investig
Viruses constitute a constant and renewed threat to humans. Not only do viruses cause
disease directly due to their tissue tropism and pathogenicity, but they have also been linked …