The comet assay: topical issues
The comet assay is a versatile and sensitive method for measuring single-and double-strand
breaks in DNA. The mechanism of formation of comets (under neutral or alkaline conditions) …
breaks in DNA. The mechanism of formation of comets (under neutral or alkaline conditions) …
The comet assay in human biomonitoring: gene–environment interactions
M Dusinska, AR Collins - Mutagenesis, 2008 - academic.oup.com
The comet assay is the method of choice for measuring DNA damage, of various sorts, in
human cells such as lymphocytes obtained in the course of population-based studies of …
human cells such as lymphocytes obtained in the course of population-based studies of …
DNA repair genetic polymorphisms and risk of colorectal cancer in the Czech Republic
B Pardini, A Naccarati, J Novotny, Z Smerhovsky… - Mutation Research …, 2008 - Elsevier
Colorectal cancer represents a complex disease where susceptibility may be influenced by
genetic polymorphisms in the DNA repair system. In the present study we investigated the …
genetic polymorphisms in the DNA repair system. In the present study we investigated the …
Genetic polymorphisms in the DNA repair genes XRCC1, XRCC2 and XRCC3 and risk of breast cancer in Cyprus
MA Loizidou, T Michael, SL Neuhausen… - Breast cancer research …, 2008 - Springer
Population-based studies have reported significant associations between specific genetic
polymorphisms and breast cancer susceptibility. A number of studies have demonstrated …
polymorphisms and breast cancer susceptibility. A number of studies have demonstrated …
Fifty years of cytogenetics: a parallel view of the evolution of cytogenetics and genotoxicology
JM Garcia-Sagredo - Biochimica et Biophysica Acta (BBA)-Gene Regulatory …, 2008 - Elsevier
A parallelism exists between human cytogenetics and cytogenetic toxicology. The
breakthroughs, mostly coming from and used in clinical genetics, are widely used in genetic …
breakthroughs, mostly coming from and used in clinical genetics, are widely used in genetic …
Associations between XPC polymorphisms and risk of cancers: A meta-analysis
L Qiu, Z Wang, X Shi, Z Wang - European Journal of Cancer, 2008 - Elsevier
Several polymorphisms (Lys939Gln, PAT+/–and Ala499Val) in the DNA nuclear excision
repair gene xeroderma pigmentosum complementation group C (XPC) are thought to have …
repair gene xeroderma pigmentosum complementation group C (XPC) are thought to have …
Modulation of DNA damage/DNA repair capacity by XPC polymorphisms
Y Zhu, H Yang, Q Chen, J Lin, HB Grossman… - DNA repair, 2008 - Elsevier
XPC, a key protein in the nucleotide excision repair (NER) pathway, recognizes damaged
DNA and initiates NER. Genetic variations in the XPC gene might be associated with altered …
DNA and initiates NER. Genetic variations in the XPC gene might be associated with altered …
hOGG1326, XRCC1399 and XRCC3241 polymorphisms influence micronucleus frequencies in human lymphocytes in vivo
RA Mateuca, M Roelants, G Iarmarcovai, PV Aka… - …, 2008 - academic.oup.com
A pooled analysis of five biomonitoring studies was performed to assess the influence of
hOGG1326, XRCC1399 and XRCC3241 gene polymorphisms on micronuclei (MN) …
hOGG1326, XRCC1399 and XRCC3241 gene polymorphisms on micronuclei (MN) …
Chromosomal aberrations in tire plant workers and interaction with polymorphisms of biotransformation and DNA repair genes
L Musak, P Soucek, L Vodickova, A Naccarati… - Mutation Research …, 2008 - Elsevier
We evaluated chromosomal aberrations in lymphocytes of 177 workers exposed to
xenobiotics in a tire plant and in 172 controls, in relation to their genetic background. Nine …
xenobiotics in a tire plant and in 172 controls, in relation to their genetic background. Nine …
The xeroderma pigmentosum group C gene polymorphisms and genetic susceptibility of nasopharyngeal carcinoma
ZH Yang, WB Liang, J Jia, YS Wei, B Zhou… - Acta …, 2008 - Taylor & Francis
Aims. Nasopharyngeal cancer (NPC) is a multi-factorial disease, and the genetic
background may be a crucial etiologic factor. The xeroderma pigmentosum …
background may be a crucial etiologic factor. The xeroderma pigmentosum …