Recurrent and second primary tumors arising within a previously radiated head and neck
volume represents a difficult clinical scenario to manage. For patients who have resectable …

Patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck
(SCCHN) have a poor prognosis, particularly those whose disease has progressed on …

Purpose: Previous investigations have suggested that a subset of patients with metastatic
cancer in a limited number of organs may benefit from local treatment. We investigated …

Background. To analyze the efficacy of various fractionation schedules for the palliation of
head and neck cancer with radiation therapy. Methods. Sixty patients completed palliative …

Although the further modification of radiotherapy and chemotherapy within
chemoradiotherapy regimens is unlikely to offer major clinical benefits, it is likely that any …

Background. The optimal treatment for patients with locally recurrent carcinomas of the
salivary glands is unclear. Methods. Ninety‐nine patients underwent salvage surgery for …

In 2002 there were about 144 000 new cases of head and neck squamous cell cancer
(HNSCC) in Europe and 69 000 deaths, making it the seventh leading cause of cancer …

Purpose: In previous studies, we have shown that the T allele of a specific single-nucleotide
polymorphism (SNP) in the Gαs gene (T393C) correlates with increased Gαs expression …

Purpose: The aim of this study was to determine the prognostic factors concerning overall
survival (OS) and progression-free survival (PFS) following reirradiation in patients with …