Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesis
Abstract Type 2 diabetes (T2DM) is characterized by insulin resistance, defective insulin
secretion, loss of β-cell mass with increased β-cell apoptosis and islet amyloid. The islet …
secretion, loss of β-cell mass with increased β-cell apoptosis and islet amyloid. The islet …
β-cell apoptosis in type 2 diabetes: quantitative and functional consequences
R Lupi, S Del Prato - Diabetes & metabolism, 2008 - Elsevier
Type 2 diabetes, the most common form of diabetes in humans, is characterized by impaired
insulin secretion paralleled by a progressive decline in β-cell function and chronic insulin …
insulin secretion paralleled by a progressive decline in β-cell function and chronic insulin …
Anaerobic exercise reduces tumor growth, cancer cachexia and increases macrophage and lymphocyte response in Walker 256 tumor-bearing rats
C de Lima, LE Alves, F Iagher, AF Machado… - European journal of …, 2008 - Springer
Here, we investigated the effect of jump exercise on tumor growth, cancer cachexia,
lymphocyte proliferation and macrophage function in Walker 256 tumor-bearing rats. Male …
lymphocyte proliferation and macrophage function in Walker 256 tumor-bearing rats. Male …
[HTML][HTML] Human islet amyloid polypeptide transgenic mice: in vivo and ex vivo models for the role of hIAPP in type 2 diabetes mellitus
JWM Höppener, HM Jacobs, N Wierup… - Experimental …, 2008 - ncbi.nlm.nih.gov
Human islet amyloid polypeptide (hIAPP), a pancreatic islet protein of 37 amino acids, is the
main component of islet amyloid, seen at autopsy in patients with type 2 diabetes mellitus …
main component of islet amyloid, seen at autopsy in patients with type 2 diabetes mellitus …
Evidence that α-calcitonin gene-related peptide is a neurohormone that controls systemic lipid availability and utilization
RN Danaher, KM Loomes, BL Leonard… - …, 2008 - academic.oup.com
α-Calcitonin gene-related peptide (αCGRP) is released mainly from sensory and motor
nerves in response to physiological stimuli. Despite well-documented pharmacological …
nerves in response to physiological stimuli. Despite well-documented pharmacological …
Treatment of diabetes with copper binding compounds
JR Baker, GJS Cooper - US Patent 7,459,446, 2008 - Google Patents
US7459446B2 - Treatment of diabetes with copper binding compounds - Google Patents
US7459446B2 - Treatment of diabetes with copper binding compounds - Google Patents …
US7459446B2 - Treatment of diabetes with copper binding compounds - Google Patents …
Phenomenological modeling of the nucleated polymerization of human islet amyloid polypeptide: a combined experimental and theoretical approach
J Bailey - 2008 - open.library.ubc.ca
The inverse scattering problem is based on the scattering theory in physics, where
measured data such as radiation from an object is used to determine the unique structure of …
measured data such as radiation from an object is used to determine the unique structure of …