Voltage-gated ion channels are crucial for both neuronal and cardiac excitability. Decades
of research have begun to unravel the intriguing machinery behind voltage sensitivity …

Phosphorylation of potassium channels affects their function and plays a major role in
regulating cell physiology. Here, we review previous studies of potassium channel …

Abstract Background The Kv2. 1 delayed-rectifier K+ channel regulates membrane
excitability in hippocampal neurons where it targets to dynamic cell surface clusters on the …

The physiological significance of neuroglial interactions in the CNS has been emphasized in
neurological conditions such as epilepsy and brain ischemia. The Kv2. 1 voltage-gated …

Focal adhesion kinase (FAK) plays key roles in cell adhesion and migration. We now report
that the delayed rectifier Kv2. 1 potassium channel, through its LD‐like motif in N‐terminus …

Voltage-gated potassium (Kv) channels comprise four transmembrane α subunits, often
associated with cytoplasmic β subunits that impact channel expression and function. Here …

The delayed-rectifier voltage-gated K+ channel (Kv) 2.1 underlies the cardiac slow K+
current in the rodent heart and is particularly interesting in that both its function and …

The last decade has witnessed an exponential increase in interest in one of the great
mysteries of nerve cell biology: Specifically, how do neurons know where to place the ion …

Kv2. 1 channels are widely expressed in neuronal and endocrine cells and generate slowly
activating K+ currents, which contribute to repolarization in these cells. Kv2. 1 is expressed …

The dynamic expression of voltage-gated potassium channels (Kvs) at the cell surface is a
fundamental factor controlling membrane excitability. In exploring possible mechanisms …