Enzymatic and non-enzymatic oxygenations of unsaturated fatty acids yield a broad family of
autocrine and paracrine cell signaling mediators. Soon after nitric oxide (NO) was described …

Hemoxygenase (HO)-1 is an inducible isoform of the first and rate-controlling enzyme of the
degradation of heme into iron, carbon monoxide, and biliverdin, the latter being …

Heme oxygenase (HO)-1 is a protective antioxidant enzyme that prevents cardiomyocyte
apoptosis, for instance, during progressive cardiomyopathy. Here we identify a fundamental …

Background HO-1 participates in the degradation of heme. Its products can exert unique
cytoprotective effects. Numerous tumors express high levels of HO-1 indicating that this …

Effect of heme oxygenase-1 on vascular function and disease : Current Opinion in Lipidology
Effect of heme oxygenase-1 on vascular function and disease : Current Opinion in Lipidology …

OBJECTIVE—We examined the effect of the vasoactive agents carbon monoxide (CO) and
nitric oxide (NO) on the phosphorylation and intracellular redistribution of vasodilator …

The discovery of C-reactive protein (CRP) almost 80 years ago in the blood of patients with
various infectious and inflammatory diseases initiated studies on the mysterious biological …

Nakao and colleagues demonstrate that carbon monoxide added to organ preservation
solution reduces donor-kidney injury that occurs after cold storage and transplantation and …

Heat shock proteins (HSPs) are primarily induced in response to stress stimuli. In
cardiovascular diseases, HSPs are expressed pronouncedly and act to protect the cardiac …

co-validation project Page 1 A report for the Department of Health NHS Stop Smoking
Service CO-verification project Sylvia May & Andy McEwen, PhD Page 2 Contents Page 1.0 …