The American Thoracic Society/European Respiratory Society jointly created a Task Force
on “Outcomes for COPD pharmacological trials: from lung function to biomarkers” to inform …

Background Systemic corticosteroids, antibiotics, and noninvasive positive pressure
ventilation (NPPV) are recommended for patients with acute exacerbation of COPD …

Rationale: Exacerbations are key drivers of morbidity and mortality in chronic obstructive
pulmonary disease (COPD). Objectives: We compared the relative efficacy of the long-acting …

Rationale: Frequent chronic obstructive pulmonary disease (COPD) exacerbations are a
major cause of hospital admission and mortality and are associated with increased airway …

Rationale: Depression and anxiety are significant comorbid and potentially modifiable
conditions in chronic obstructive pulmonary disease (COPD), but their effects on …

Rationale: Unreported exacerbations and failure to seek medical attention may have
consequences on the health of patients with chronic obstructive pulmonary disease …

Rationale: Much of the total disease burden and cost of chronic obstructive pulmonary
disease (COPD) is associated with acute exacerbations of COPD (AECOPD). Serum …

OBJECTIVES: COPD exacerbations are associated with significant morbidity and mortality.
This randomized, double-blind, parallel-group, multicenter study evaluated the effect of …

Background COPD is characterized by episodic increases in respiratory symptoms, so-
called exacerbations. COPD exacerbations are associated with an increase in local and …

Chronic obstructive pulmonary disease is associated with exacerbations. Some patients are
prone to frequent exacerbations and these individuals have a worse quality of life, greater …