S Systematic reviews of controlled trials are the gold standard for decision-making and
appear at the top of the hierarchy of evidence about effectiveness. They can and should …

Typeset in 10.5/12.5 pt Times by Aptara Inc., New Delhi, India Printed and bound in Great
Britain by Antony Rowe Ltd, Chippenham, Wiltshire This book is printed on acid-free paper …

Past studies have reported high success rates for cerclage for the prevention of preterm
labor in women with cervical incompetence. However, a recent Cochrane review found no …

In this book the author explores the shifting philosophical boundaries of modern medical
knowledge and practice occasioned by the crisis of quality-of-care, especially in terms of the …

Meta-analysis, the statistical combination of results from several studies to produce a single
estimate of a treatment effect or size of an association, continues to attract controversy. We …

Meta-analysis can be a powerful tool for demonstrating the applicability of a concept beyond
the context of individual clinical trials and observational studies, including exploration of …

In the past, women with early-stage cervical cancer have been treated with radical
radiotherapy or radical surgery, and women with locally advanced disease with radical …

Objective: To assess agreement between Cochrane Neonatal Group reviews and clinical
practice guidelines in Denmark. Design: Retrospective analysis of clinical guidelines for …

Evidence-based medicine (EBM) involves using research data to enhance the diagnosis
and treatment of clinical disorders. Somatic dysfunction and osteopathic manipulative …

Manic–depressive disorders are recurrent, major mood disorders that, if untreated, lead to
substantial morbidity. Neurobiologic and psychosocial models have been applied to explain …