Abstract CD133 (prominin‐1) was the first in a class of novel pentaspan membrane proteins
to be identified in both humans and mice, and was originally classified as a marker of …

Abstract Human CD133 (human prominin-1), a five transmembrane domain glycoprotein,
was originally identified as a cell surface antigen present on CD34+ hematopoietic stem …

Here, we demonstrate self-organized formation of apico-basally polarized cortical tissues
from ESCs using an efficient three-dimensional aggregation culture (SFEBq culture). The …

Neural stem cells (NSCs, B1 cells) are retained in the walls of the adult lateral ventricles but,
unlike embryonic NSCs, are displaced from the ventricular zone (VZ) into the subventricular …

Colon cancer stem cells are believed to originate from a rare population of putative CD133+
intestinal stem cells. Recent publications suggest that a small subset of colon cancer cells …

Purpose: The CD133 antigen has been identified as a putative stem cell marker in normal
and malignant brain tissues. In gliomas, it is used to enrich a subpopulation of highly …

OBJECTIVE: Several studies have shown that human gliomas contain a small population of
cells with stem cell-like features. It has been proposed that these “cancer stem cells” may be …

Aim Gliomas represent the most frequent neoplasm of the central nervous system.
Unfortunately, surgical cure of it is practically impossible and their clinical course is primarily …

Background Osteosarcoma is the most common primary tumour of bone. Solid tumours are
made of heterogeneous cell populations, which display different goals and roles in tumour …

Familial macular degeneration is a clinically and genetically heterogeneous group of
disorders characterized by progressive central vision loss. Here we show that an R373C …