Human herpes virus 6B: a possible role in epilepsy?
Summary Human herpes virus 6 (HHV6) infection is nearly ubiquitous in childhood and may
include central nervous system invasion. There are two variants, HHV6A and HHV6B …
include central nervous system invasion. There are two variants, HHV6A and HHV6B …
Defining the spectrum of international practice in pediatric epilepsy surgery patients
AS Harvey, JH Cross, S Shinnar, GW Mathern… - …, 2008 - Wiley Online Library
Summary Purpose: The Pediatric Epilepsy Surgery Sub‐commission of the International
League Against Epilepsy conducted a survey to determine the frequency of epilepsy …
League Against Epilepsy conducted a survey to determine the frequency of epilepsy …
Therapeutic approaches to ion channel diseases
DC Camerino, JF Desaphy, D Tricarico, S Pierno… - Advances in …, 2008 - Elsevier
More than 400 genes are known that encode ion channel subunits. In addition, alternative
splicing and heteromeric assembly of different subunits increase tremendously the variety of …
splicing and heteromeric assembly of different subunits increase tremendously the variety of …
FASTKD2 nonsense mutation in an infantile mitochondrial encephalomyopathy associated with cytochrome c oxidase deficiency
In two siblings we found a mitochondrial encephalomyopathy, characterized by
developmental delay, hemiplegia, convulsions, asymmetrical brain atrophy, and low …
developmental delay, hemiplegia, convulsions, asymmetrical brain atrophy, and low …
Speaking with a single cerebral hemisphere: fMRI language organization after hemispherectomy in childhood
Speech-related fMRI activation was examined in six hemispherectomy patients (three left
LX, three right RX, four with congenital and two with late-acquired hemiplegia) operated in …
LX, three right RX, four with congenital and two with late-acquired hemiplegia) operated in …
Autoantibodies to glutamate receptors can damage the brain in epilepsy, systemic lupus erythematosus and encephalitis
M Levite, Y Ganor - Expert review of neurotherapeutics, 2008 - Taylor & Francis
Glutamate is the major excitatory CNS neurotransmitter. Glutamate receptor autoantibodies
have now been called to our attention, as they are found in many patients with epilepsy …
have now been called to our attention, as they are found in many patients with epilepsy …
Language after hemispherectomy in childhood: contributions from memory and intelligence
F Liégeois, JH Cross, C Polkey, W Harkness… - Neuropsychologia, 2008 - Elsevier
After hemispherectomy (removal or disconnection of an entire cerebral hemisphere) in
childhood for treatment of intractable epilepsy, gross speech and language functions are …
childhood for treatment of intractable epilepsy, gross speech and language functions are …
Autoantibodies to Munc18, cerebral plasma cells and B-lymphocytes in Rasmussen encephalitis
Rasmussen encephalitis (RE) is a rare form of severe unihemispheric epilepsy established
to be an autoimmune disease. Here we demonstrate the presence of autoantibodies against …
to be an autoimmune disease. Here we demonstrate the presence of autoantibodies against …
Diagnostic and pathogenic significance of glutamate receptor autoantibodies
D Pleasure - Archives of Neurology, 2008 - jamanetwork.com
Autoantibodies against glutamate receptors, first reported in Rasmussen encephalitis, have
been observed in other focal epilepsies, central nervous system ischemic infarcts, transient …
been observed in other focal epilepsies, central nervous system ischemic infarcts, transient …
Rasmussen encephalitis associated with SCN1A mutation
I Ohmori, M Ouchida, K Kobayashi, Y Jitsumori… - …, 2008 - Wiley Online Library
Mutations in the SCN1A gene, encoding the neuronal voltage‐gated sodium channel α1
subunit, cause SMEI, GEFS+, and related epileptic syndromes. We herein report the …
subunit, cause SMEI, GEFS+, and related epileptic syndromes. We herein report the …