Thirty years of brain imaging research has converged to define the brain's default network—
a novel and only recently appreciated brain system that participates in internal modes of …

Multiple sclerosis (MS) has been classically regarded as a white matter disease. However,
recent histopathological studies have convincingly shown that grey matter regions are also …

Two functionally distinct, and potentially competing, brain networks have been recently
identified that can be broadly distinguished by their contrasting roles in attention to the …

Recent research has shown that intrinsic brain activity as observed by functional magnetic
resonance imaging (fMRI) manifest itself as coherent signal changes in networks …

Normal aging is associated with cognitive decline. Functions such as attention, information
processing, and working memory are compromised. It has been hypothesized that not only …

Increased intraindividual variability (IIV) is a hallmark of disorders of attention. Recent work
has linked these disorders to abnormalities in a “default mode” network, comprising brain …

Classically regarded as motor structures, the basal ganglia subserve a wide range of
functions, including motor, cognitive, motivational, and emotional processes. Consistent with …

BACKGROUND: Pathophysiologic models of attention-deficit/hyperactivity disorder (ADHD)
have focused on frontal-striatal circuitry with alternative hypotheses relatively unexplored …

The brain is a complex dynamic system of functionally connected regions. Graph theory has
been successfully used to describe the organization of such dynamic systems. Recent …

Neural activity fluctuates dynamically with time, and these changes have been reported to
be of behavioral significance, despite occurring spontaneously. Through …