[HTML][HTML] Glutamate receptor activation triggers OPA1 release and induces apoptotic cell death in ischemic rat retina
WK Ju, JD Lindsey, M Angert, A Patel… - Molecular vision, 2008 - ncbi.nlm.nih.gov
Purpose Glutamate receptor activation-induced excitotoxicity has been hypothesized to
cause retinal ganglion cell (RGC) death in glaucoma and to link mitochondrial dysfunction in …
cause retinal ganglion cell (RGC) death in glaucoma and to link mitochondrial dysfunction in …
Comprehensive cDNA study and quantitative transcript analysis of mutant OPA1 transcripts containing premature termination codons
S Schimpf, N Fuhrmann, S Schaich… - Human mutation, 2008 - Wiley Online Library
Autosomal dominant optic atrophy (adOA) is most commonly caused by mutations in the
OPA1 gene. There is a considerable allelic heterogeneity among adOA‐associated OPA1 …
OPA1 gene. There is a considerable allelic heterogeneity among adOA‐associated OPA1 …
[HTML][HTML] Identification of two novel OPA1 mutations in Chinese families with autosomal dominant optic atrophy
Y Li, T Deng, Y Tong, S Peng, B Dong, D He - Molecular Vision, 2008 - ncbi.nlm.nih.gov
Purpose To report the clinical features and identification of two novel mutations in two
Chinese pedigrees with autosomal dominant optic atrophy (ADOA). Methods Two families …
Chinese pedigrees with autosomal dominant optic atrophy (ADOA). Methods Two families …
青光眼的分子遗传学研究现状
沈降， 刘伟民， 孙慧敏 - 中国实用眼科杂志, 2008 - cqvip.com
青光眼是目前最主要的致盲性眼病之一. 在40 岁以上的人群中, 其患病率达2% 以上. 目前,
青光眼的病因尚未阐明, 但越来越多的证据表明青光眼是一种多因素多基因的疾病. 迄今 …
青光眼的病因尚未阐明, 但越来越多的证据表明青光眼是一种多因素多基因的疾病. 迄今 …
Inherited Optic Neuropathies
M Votruba - Pediatric Ophthalmology, Neuro-Ophthalmology …, 2008 - Springer
Inherited optic neuropathies are a diverse group of conditions presenting with mild to severe
visual loss, colour vision deficits, central/paracentral visual field defects, optic disc pallor and …
visual loss, colour vision deficits, central/paracentral visual field defects, optic disc pallor and …
Biogenese des Dynamin-ähnlichen Proteins OPA1 in Mitochondrien
J Wagener - 2008 - edoc.ub.uni-muenchen.de
Ein Charakteristikum der Mitochondrien ist das Vorhandensein eines eigenen
mitochondrialen Genoms (mitochondriale DNA; mtDNA), eine Tatsache, die durch die …
mitochondrialen Genoms (mitochondriale DNA; mtDNA), eine Tatsache, die durch die …