[HTML][HTML] The Role of the Iron Transporter ABCB7 in Refractory Anemia with Ring Sideroblasts

J Boultwood, A Pellagatti, M Nikpour, B Pushkaran… - PloS one, 2008 - journals.plos.org
Refractory Anemia with Ring Sideroblasts (RARS) is an acquired myelodysplastic syndrome
(MDS) characterized by an excess iron accumulation in the mitochondria of erythroblasts …

Direct interactions between the Paf1 complex and a cleavage and polyadenylation factor are revealed by dissociation of Paf1 from RNA polymerase II

K Nordick, MG Hoffman, JL Betz, JA Jaehning - Eukaryotic cell, 2008 - Am Soc Microbiol
ABSTRACT The Paf1 complex (Paf1, Ctr9, Cdc73, Rtf1, and Leo1) is normally associated
with RNA polymerase II (Pol II) throughout the transcription cycle. However, the loss of either …

[HTML][HTML] Structure and DNA binding of the human Rtf1 Plus3 domain

RN de Jong, V Truffault, T Diercks, AB Eiso… - Structure, 2008 - cell.com
The yeast Paf1 complex consists of Paf1, Rtf1, Cdc73, Ctr9, and Leo1 and regulates histone
H2B ubiquitination, histone H3 methylation, RNA polymerase II carboxy-terminal domain …

Multiple yeast genes, including Paf1 complex genes, affect telomere length via telomerase RNA abundance

AD Mozdy, ER Podell, TR Cech - Molecular and cellular biology, 2008 - Am Soc Microbiol
Twofold reductions in telomerase RNA levels cause telomere shortening in both humans
and the yeast Saccharomyces cerevisiae. To test whether multiple genes that affect telomere …

[PDF][PDF] Transcriptional regulation: it takes a village

B Panning, DJ Taatjes - Molecular cell, 2008 - cell.com
A FASEB conference on" Transcriptional Regulation during Cell Growth, Differentiation and
Development" met in June, 2008, just outside of Aspen in Snowmass Village, Colorado. The …

[HTML][HTML] Autoantigenic nuclear proteins of a clinically atypical renal vasculitis

J Avila, E Acosta, MV Machargo, MF Arteaga… - Journal of autoimmune …, 2008 - Springer
Background Systemic vasculitides constitute a heterogeneous group of diseases of
autoimmunological origin characterized by inflammation of blood vessels and antibodies …