Parkinson's disease (PD) is a progressive neurodegenerative movement disorder and in
most patients its aetiology remains unknown. Molecular genetic studies in familial forms of …

Parkinson's disease is a common progressive neurodegenerative disorder caused by the
loss of dopaminergic neurons in the substantia nigra. We investigated whether cell therapy …

In Parkinson disease, wild-type α-synuclein accumulates during aging, whereas α-synuclein
mutations lead to an early onset and accelerated course of the disease. The generation of …

In one genetic study, the high temperature requirement A2 (HTRA2) mitochondrial protein
has been associated with increased risk for sporadic Parkinson disease (PD). One missense …

Parkinson's disease (PD) is a neurological disorder characterized by the progressive
impairment of motor skills in patients. Growing evidence suggests that abnormal redox …

Inadequate dietary n-3 polyunsaturated fatty acid (PUFA) content is associated with altered
function of the CNS dopamine systems. In this study, the effects of dietary n-3 PUFA content …

Ropinirole, a D2/D3 receptor agonist has been reported to have neuroprotective effects. We
showed that ropinirole can prevent rotenone-induced apoptosis in dopaminergic cell line SH …

Parkinson's disease (PD) is a progressive neurodegenerative disorder for which there is no
current therapy preventing cumulative neuronal loss. There is substantial evidence that …

Parkinson's disease (PD) is a neurodegenerative disorder affecting nearly 3 million patients
in Europe and North America, characterized by a core phenotype of motor deficits, akinesia …

APOPTOSIS or programmed cell death is a gene regulated phenomenon which is important
in both physiological and pathological conditions. It is characterized by distinct …