Ischemia has been an inevitable event accompanying kidney transplantation. Ischemic
changes start with brain death, which is associated with severe hemodynamic disturbances …

In metazoans apoptosis is a major physiological process of cell elimination during
development and in tissue homeostasis and can be involved in pathological situations. In …

Hydrogen sulfide (H2S) is an endogenously produced gaseous signaling molecule with
diverse physiological activity. The potential protective effects of H2S have not been …

The amphipathic molecule dimethyl sulphoxide (DMSO) is a solvent often used to dissolve
compounds applied to the inner ear; however, little is known about its potential cytotoxic side …

Apoptosis has been considered as an underlying mechanism in acute lung injury/acute
respiratory distress syndrome and multiorgan dysfunction syndrome. Recently, several …

Background & Aims: Acute liver insufficiency is a rare complication of anorexia nervosa. The
mechanisms for this complication are unclear. The aim of this study was to describe patient …

Autophagy selectively removes abnormal or damaged organelles such as dysfunctional
mitochondria. The mitochondrial permeability transition (MPT) is a marker of impaired …

Mitochondria generate reactive oxygen and peroxynitrite and release endonucleases during
acetaminophen (APAP) hepatotoxicity. Because mitochondrial translocation of Bax can …

Acute liver failure (ALF) occurs when the extent of hepatocyte death exceeds the liver's
regenerative capacity. Despite vast differences in causes, the mode of cell death typically …

Graft failure after liver transplantation may involve mitochondrial dysfunction. We examined
whether prevention of mitochondrial injury would improve graft function. Orthotopic rat liver …