Transcription factors initiate programs of gene expression and are catalysts in downstream
molecular cascades that modulate a variety of cellular processes. Pax3 is a transcription …

Anatomically widely different designs of animal eyes have long been thought to arise
independently multiple times during evolution. This morphology-based view has been …

SUMMARY A homozygous substitution of the highly conserved isoleucine at position 26 by
threonine (I26T) in the transcriptional repressor HESX1 has been associated with anterior …

The solution structure of the complex between the transcription factor PhoB DNA‐
binding/transactivation domain and DNA was determined by NMR spectroscopy and …

Pax7 plays critical roles in development of brain, spinal cord, neural crest, and skeletal
muscle. As a sequence-specific DNA-binding transcription factor, any direct functional role …

Many transcription factors alter DNA or chromatin structure. Changes in chromatin structure
are often brought about by the recruitment of chromatin-binding proteins, chromatin …

Motivation: Transcription factor interactions are the cornerstone of combinatorial control,
which is a crucial aspect of the gene regulatory system. Understanding and predicting …

Two formacetal‐linked dinucleotides TT and TA were synthesized as phosphoramidite
building blocks for solid‐phase synthesis. Incorporated in a 29‐mer DNA, the oligomers …

Abstract<? Pub Inc> Eukaryotic DNA-binding proteins mediate many important steps in
embryonic development and gene regulation. Consequently, a better understanding of …

A vast majority of known studies of protein-DNA complexes are related to the binding site of
proteins with double-stranded DNA in the B-form in the region of its major groove [1Ä9]. In …