Thyroid cancer is the most common malignant tumor of the endocrine system and accounts
for approximately 1% of all newly diagnosed cancer cases. The most frequent type of thyroid …

There is now a reasonably good understanding of the key oncogenic events involved in the
initiation and progression of thyroid cancer. Many of these are characteristic of certain tumor …

Abstract BRAF (V600E) mutation is the most frequent genetic alteration in papillary thyroid
carcinomas (PTCs) that are 80–90% of all thyroid cancers. We evaluated the relationship …

Micro RNAs (miRNAs) are non‐coding small RNAs and constitute a novel class of negative
gene regulators that are found in both plants and animals. Several miRNAs play crucial …

BRAF-activating mutations have been reported in several types of cancer, including
melanoma (∼ 70% of cases), thyroid (30-70%), ovarian (15-30%), and colorectal cancer (5 …

Using gene expression profiling, we found that the CBX7 gene was drastically down-
regulated in six thyroid carcinoma cell lines versus control cells. The aims of this study were …

The close genotype-phenotype relationship that characterizes thyroid oncology stimulated
the authors to address this article by using a mixed, genetic and phenotypic approach. As …

Background A fine needle aspiration (FNA) diagnosis of a Hürthle cell neoplasm is
associated with a 20% risk of malignancy. We sought to determine if the primary tumor size …

Loss of ABI gene family member 3-binding protein (ABI3BP) expression may be functionally
involved in the pathogenesis of cancer. Previous reports have indicated a loss of expression …

In this study, we evaluated the activity of two novel pyrazolopyrimidine derivatives (Si 34 and
Si 35) against ARO cells, a human anaplastic thyroid cancer cell line. ARO cells exposed to …