Status and prospects of association mapping in plants

C Zhu, M Gore, ES Buckler, J Yu - The plant genome, 2008 - Wiley Online Library
There is tremendous interest in using association mapping to identify genes responsible for
quantitative variation of complex traits with agricultural and evolutionary importance. Recent …

Catechol-O-methyltransferase (COMT): a gene contributing to sex differences in brain function, and to sexual dimorphism in the predisposition to psychiatric disorders

PJ Harrison, EM Tunbridge - Neuropsychopharmacology, 2008 - nature.com
Sex differences in the genetic epidemiology and clinical features of psychiatric disorders are
well recognized, but the individual genes contributing to these effects have rarely been …

[图书][B] Neurobiology of violence

J Volavka - 2008 - books.google.com
Every clinician today needs a basic understanding of what causes violent behavior. The
second edition of Neurobiology of Violence synthesizes current research on the origins of …

Gender differences in obsessive–compulsive symptom dimensions

J Labad, JM Menchon, P Alonso… - Depression and …, 2008 - Wiley Online Library
The aim of our study was to assess the role of gender in OCD symptom dimensions with a
multivariate analysis while controlling for history of tic disorders and age at onset of OCD …

Crystal structures of human 108V and 108M catechol O-methyltransferase

K Rutherford, I Le Trong, RE Stenkamp… - Journal of molecular …, 2008 - Elsevier
Catechol O-methyltransferase (COMT) plays important roles in the metabolism of
catecholamine neurotransmitters and catechol estrogens. The development of COMT …

[HTML][HTML] Glutamatergic synaptic dysfunction and obsessive-compulsive disorder

JT Ting, G Feng - Current chemical genomics, 2008 - ncbi.nlm.nih.gov
Obsessive-compulsive disorder (OCD) is a debilitating neuropsychiatric condition estimated
to afflict 1-3% of the world population. The estimated financial impact in the treatment and …

Genetic and environmental influences on obsessive-compulsive disorder

JR Grisham, TM Anderson, PS Sachdev - European archives of psychiatry …, 2008 - Springer
It is important to understand how genetic and environmental factors interact in the
development of obsessive-compulsive disorder (OCD) in order to provide a cohesive model …

Extensive genotyping of the BDNF and NTRK2 genes define protective haplotypes against obsessive-compulsive disorder

P Alonso, M Gratacòs, JM Menchón, J Saiz-Ruiz… - Biological …, 2008 - Elsevier
BACKGROUND: Family, twin and molecular studies provide increasing evidence for the
importance of genetic factors in obsessive-compulsive disorder (OCD). Recent work …

Neurophysiological and genetic distinctions between pure and comorbid anxiety disorders

MA Enoch, KV White, J Waheed… - Depression and …, 2008 - Wiley Online Library
Anxiety disorders are often comorbid with major depression (MD) and alcohol use disorders
(AUD). Two common functional polymorphisms in catechol‐O‐methyltransferase (COMT …

Genetics of anxiety: would the genome recognize the DSM?

JW Smoller, E Gardner‐Schuster… - Depression and …, 2008 - Wiley Online Library
The nosology of anxiety disorders has undergone substantial evolution over the past several
decades. The modern classification of these disorders dates to the publication of Diagnostic …