New technologies for imaging molecules, particularly optical technologies, are increasingly
being used to understand the complexity, diversity and in vivo behaviour of cancers.'Omic' …

Molecular imaging can allow the non-invasive assessment of biological and biochemical
processes in living subjects. Such technologies therefore have the potential to enhance our …

A tutorial introduction to diffuse light transport is presented. The basic analytic equations of
time-resolved, steady-state and modulated light transport are introduced. The perturbation …

A multichannel spectrally resolved optical tomography system to image molecular targets in
small animals from within a clinical MRI is described. Long source/detector fibers operate in …

Raman spectroscopic diffuse tomographic imaging has been demonstrated for the first time.
It provides a noninvasive, label-free modality to image the chemical composition of human …

Autofluorescence is a nuisance in the field of fluorescence imaging and tomography of
exogenous molecular markers in tissue, degrading the quality of the collected data. In this …

The ability to visualize molecular processes and cellular regulators of complex pulmonary
diseases such as asthma, chronic obstructive pulmonary disease (COPD), or adult …

We present in vivo experiments conducted with a new fluorescence diffuse optical
tomographic (fDOT) system on cancerous mice bearing mammary murine tumors. We first …

With evidence emerging in support of a cancer stem-cell model of carcinogenesis, it is of
paramount importance to identify and image these elusive cells in their natural environment …

Recent advances in molecular imaging have permitted the noninvasive imaging of
apoptosis, a critical process underlying the pathogenesis of many diseases of the …