Background Much controversy exists regarding the clinical efficacy of behavioural and
developmental interventions for improving the core symptoms of autism spectrum disorders …

Context Acute renal failure requiring dialytic support is associated with a high risk of
mortality and substantial morbidity. Objectives To summarize current evidence guiding …

The second edition of this best-selling book has been thoroughly revised and expanded to
reflect the significant changes and advances made in systematic reviewing. New features …

Background Previous studies of drug trials submitted to regulatory authorities have
documented selective reporting of both entire trials and favorable results. The objective of …

Objective: To provide a descriptive overview of the clinical trials assessing meditation
practices for health care. Design: Systematic review of the literature. Comprehensive …

Clinical practice guidelines are systematically developed statements that aim to help
physicians and patients reach the best health care decisions. Appropriately developed …

BACKGROUND: Observational studies indicate that routine measurements of access blood
flow and use of Doppler ultrasound improve vascular access outcomes in hemodialysis …

Multiple types of controlled trials include placebo-controlled and pragmatic trials. Placebo-
controlled RCTs have multiple shortcomings such as cost and length, which limit the …

This review concluded that there was insufficient evidence to identify a particular diabetes
education intervention targeted at children with type 1 diabetes and/or their families that was …

This article analyses the role of the pharmaceutical and medical device industries ('pharma')
in the construction of scientific and medical knowledge. Pharma's activities are part of the …