Guidance is provided in a European setting on the assessment and treatment of
postmenopausal women with or at risk from osteoporosis. Introduction The European …

Recent clinical data on selective estrogen receptor modulators (SERMs) have provided the
basis for reassessment of the SERM concept. The molecular basis of SERM activity involves …

Background Tibolone has estrogenic, progestogenic, and androgenic effects. Although
tibolone prevents bone loss, its effects on fractures, breast cancer, and cardiovascular …

Due to the high incidence of breast cancer among US females, risk‐reduction strategies are
essential. Before considering approaches to breast cancer risk reduction, it is important for …

Osteoporosis affects millions of people worldwide, causing decreases in bone strength and
a marked increase in fracture risk. Current therapies increase bone mineral density and …

The National Institute for Health and Clinical Excellence (NICE) in the UK has recently
issued health economic appraisals for the primary and secondary prevention of osteoporotic …

The metastasis of cancer cells to bone alters bone architecture and mineral homeostasis. As
described by the 'seed and soil'hypothesis, bone represents a fertile ground for cancer cells …

[Frontiers in Bioscience 13, 3273-3287, May 1, 2008] 3273 The type I insulin-like growth factor
receptor pathway: a key player i Page 1 [Frontiers in Bioscience 13, 3273-3287, May 1, 2008] …

Objective To evaluate the cost-effectiveness of osteoporosis treatments for women at high
fracture risk and estimate the population-level impact of providing bisphosphonate therapy …

En el año 2001 se presentaron las Guías de Práctica Clínica sobre Osteoporosis
Posmenopáusica de la Sociedad Española de Investigación Ósea y del Metabolismo …