Purpose: Overexpression of extracellular matrix metalloproteinase inducer (EMMPRIN), a
member of the immunoglobulin family and a glycoprotein enriched on the surface of many …

CD147, also named as extracelluar matrix metalloproteinase inducer (EMMPRIN), has been
proved to be involved in several aspects of tumor progression. In addition to its ability to …

Background: Multidrug-resistant cancer cells overexpressing P-glycoprotein (P-gp) display
variations in invasive and metastatic ability through the upregulation of the extracellular …

Aims and Background The role of heat shock protein (HSP) 70 in gastric cancer has been
extensively examined in many studies for the past decade. It has been demonstrated that …

There is a correlation between the multidrug-resistance (MDR) of cancer cells and their
enhanced invasive or metastatic potential. We studied the expression of CD147, a plasma …

Multidrug resistant (MDR) tumor cells over-expressing P-glycoprotein exhibit variation in
invasive behavior. To investigate the mechanisms, we analyzed the expression of CD147 …

Background Expression of intracellular antibodies (intrabodies) has become a broadly
applicable technology for generation of phenotypic knockouts in vivo. The method uses …

CD147 plays a critical role in the invasive and metastatic activity of hepatocellular carcinoma
(HCC) cells by stimulating the surrounding fibroblasts to secrete matrix metalloproteinases …

Commentary to: Stereomicroscopic fluorescence imaging of head and neck cancer
xenografts targeting CD147 J. Robert Newman, John P. Gleysteen, Christopher F …

MCT4 is a heteromeric proton-coupled lactate transporter that is non-covalently linked to the
extracellular matrix metalloproteinase inducer, CD147 and is typically expressed in …