More and more systematic reviews of diagnostic test accuracy studies are being published,
but they can be methodologically challenging. In this paper, the authors present some of the …

Aim: Elevated plasma C‐reactive protein (CRP) is regarded as a risk predictor for
cardiovascular diseases. This systematic review explored the robustness of observations …

Such diverse thinkers as Lao-Tze, Confucius, and US Defense Secretary Donald Rumsfeld
have all pointed out that we need to be able to tell the difference between real and assumed …

BACKGROUND Sperm DNA damage is common amongst infertile men and may adversely
impact natural reproduction, IUI-assisted reproduction and to a lesser degree IVF …

Background: A sensitive and acceptable screening regimen for women at high risk for breast
cancer is essential. Contrast-enhanced magnetic resonance imaging (MRI) of the breast is …

BACKGROUND: Conventional tests are not always helpful in making a diagnosis of
tuberculous pleurisy. Many studies have investigated the usefulness of adenosine …

The global extensively drug-resistant tuberculosis (TB) response plan calls for
implementation of rapid tests to screen patients at risk of drug-resistant TB. Currently, two …

Purpose: To perform a meta-analysis to estimate the diagnostic accuracy of dynamic
contrast material–enhanced computed tomography (CT) and magnetic resonance (MR) …

Abstract Context: The diagnosis of Cushing's syndrome (CS) requires the use of tests of
unregulated hypercortisolism that have unclear accuracy. Objective: Our objective was to …

Background Hundreds of studies have evaluated the diagnostic accuracy of nucleic-acid
amplification tests (NAATs) for tuberculosis (TB). Commercial tests have been shown to give …