• Insomnia is a major source of distress to people with chronic pain; many of whom
presenting for treatment want tangible help with sleep.• Compared to chronic pain patients …

Cross-sectional research in clinical samples, as well as experimental studies in healthy
adults, suggests that the experiences of pain and sleep are bi-directionally connected …

People with fibromyalgia syndrome (FMS) experi-ence unrefreshing sleep, aches,
hypersensitivity, and cognitive and emotional difficulties. Although no specific causative …

Both cross-sectional studies of chronic pain and sleep deprivation experiments suggest a bi-
directional relationship between sleep and pain. Few longitudinal studies, however, have …

Sleep complaints are especially common in survivors of childhood cancer who have
sustained an injury to the hypothalamus or brainstem, have evidence of endocrine …

Abstract Study Objectives: The trigeminal nuclear complex (V) contains cholinergic neurons
and includes the principal sensory trigeminal nucleus (PSTN) which receives sensory input …

Pain is the most common complaint amongst all patients seeking care from all types of
health practitioners. It is estimated that 40% of patient visits to health care practitioners are …

Assessment of quality of life (QOL) is important in evaluating the well-being of patients
suffering from chronically painful conditions. In addition to identifying the degree of …

Sleep quality and sleep duration affect pain thresholds in experimental models, and in
clinical practice changes in sleep can cause or trigger headache. Obstructive sleep apnea is …

Objectives: To review 1. the animal and human experimental evidence that implicates
disordered sleep/wake physiology in the etiology of widespread pain and fatigue and 2. the …