Background: Obesity is a well-known cause of cardiovascular disease burden and
premature death, but effects on psychological morbidity remain uncertain. This article reports …

It is increasingly clear that significant differential regulation of pituitary and adrenal gland
activation exists, leading to a dissociation of plasma adrenocorticotropic hormone and …

Background: Obesity is a well-known cause of cardiovascular disease burden and
premature death, but effects on depressive symptoms remain equivocal. Depressive …

Affective disorders such as major depression are among the most prevalent and costly
diseases of the central nervous system, but the underlying mechanisms are still poorly …

BACKGROUND: Pain experienced by people with knee osteoarthritis is related to
psychosocial factors and damage to articular tissues and/or the pain pathway itself …

Recent lines of research suggest that, in addition to hypothalamic sites, the striatum
dopaminergic system may be a target for regulating homeostasis that may be represented …

Arterial hypertension is a frequent and leading cardiovascular risk factor, and primary
aldosteronism is a well-recognized cause of secondary hypertension. Aldosterone is the …

Over 2000 years ago, the philosopher Aristotle issued a simple, yet prescient thesis,
writing,“Society is something in nature that precedes the individual.” Aristotle's notion is one …

OBJECTIVES: To examine in patients with mood disorders the relationship of age at onset
with the location and degree of MRI-defined brain hyperintensities. METHOD: Fifty-two …

Recently, it has become evident that the adrenals play a key role in obesity as well as in the
metabolic syndrome and their complications. On the one hand, adrenal steroids are involved …