MicroRNAs: new regulators of immune cell development and function
D Baltimore, MP Boldin, RM O'connell, DS Rao… - Nature …, 2008 - nature.com
Decades of research went into understanding immune cell development and function
without awareness that consideration of a key element, microRNA (miRNA), was lacking …
without awareness that consideration of a key element, microRNA (miRNA), was lacking …
Small non-coding RNAs in animal development
The modulation of gene expression by small non-coding RNAs is a recently discovered level
of gene regulation in animals and plants. In particular, microRNAs (miRNAs) and Piwi …
of gene regulation in animals and plants. In particular, microRNAs (miRNAs) and Piwi …
Widespread changes in protein synthesis induced by microRNAs
Animal microRNAs (miRNAs) regulate gene expression by inhibiting translation and/or by
inducing degradation of target messenger RNAs. It is unknown how much translational …
inducing degradation of target messenger RNAs. It is unknown how much translational …
The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesis
S Wang, AB Aurora, BA Johnson, X Qi, J McAnally… - Developmental cell, 2008 - cell.com
Endothelial cells play essential roles in maintenance of vascular integrity, angiogenesis, and
wound repair. We show that an endothelial cell-restricted microRNA (miR-126) mediates …
wound repair. We show that an endothelial cell-restricted microRNA (miR-126) mediates …
The microRNA. org resource: targets and expression
Abstract MicroRNA. org (http://www. microrna. org) is a comprehensive resource of
microRNA target predictions and expression profiles. Target predictions are based on a …
microRNA target predictions and expression profiles. Target predictions are based on a …
MicroRNA-10a binds the 5′ UTR of ribosomal protein mRNAs and enhances their translation
MicroRNAs (miRNAs) are small RNAs that function as posttranscriptional regulators of gene
expression. miRNAs affect a variety of signaling pathways, and impaired miRNA regulation …
expression. miRNAs affect a variety of signaling pathways, and impaired miRNA regulation …
Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells
MicroRNAs (miRNAs) are crucial for normal embryonic stem (ES) cell self-renewal and
cellular differentiation, but how miRNA gene expression is controlled by the key …
cellular differentiation, but how miRNA gene expression is controlled by the key …
Discovering microRNAs from deep sequencing data using miRDeep
The capacity of highly parallel sequencing technologies to detect small RNAs at
unprecedented depth suggests their value in systematically identifying microRNAs …
unprecedented depth suggests their value in systematically identifying microRNAs …
An analysis of human microRNA and disease associations
It has been reported that increasingly microRNAs are associated with diseases. However,
the patterns among the microRNA-disease associations remain largely unclear. In this study …
the patterns among the microRNA-disease associations remain largely unclear. In this study …
MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1
Adhesion molecules expressed by activated endothelial cells play a key role in regulating
leukocyte trafficking to sites of inflammation. Resting endothelial cells normally do not …
leukocyte trafficking to sites of inflammation. Resting endothelial cells normally do not …