Safety and efficacy of alefacept, efalizumab, etanercept and infliximab in treating moderate to severe plaque psoriasis: a meta‐analysis of randomized controlled trials

AK Brimhall, LN King, JC Licciardone… - British Journal of …, 2008 - academic.oup.com
Background The relatively recent introduction of biological agents to treat psoriasis presents
clinicians with the need to objectively compare and contrast these agents to allow more …

Mapping the moral terrain of clinical research

S Joffe, FG Miller - Hastings Center Report, 2008 - Wiley Online Library
Medical research is widely thought to have a fundamentally therapeutic orientation, in spite
of the fact that clinical research is thought to be ethically distinct from medical care. We need …

Explicit teaching of meta-strategic knowledge in authentic classroom situations

A Zohar, AB David - Metacognition and learning, 2008 - Springer
Meta-strategic Knowledge (MSK) is a sub-component of metacognition that is defined in the
present study as general, explicit knowledge about thinking strategies. In the present study …

Treatment success in cancer: new cancer treatment successes identified in phase 3 randomized controlled trials conducted by the National Cancer Institute …

B Djulbegovic, A Kumar, HP Soares… - Archives of internal …, 2008 - jamanetwork.com
Background The evaluation of research output, such as estimation of the proportion of
treatment successes, is of ethical, scientific, and public importance but has rarely been …

Simple, defensible sample sizes based on cost efficiency

P Bacchetti, CE McCulloch, MR Segal - Biometrics, 2008 - academic.oup.com
The conventional approach of choosing sample size to provide 80% or greater power
ignores the cost implications of different sample size choices. Costs, however, are often …

[图书][B] Clinical trials in psychiatry

BS Everitt, S Wessely - 2008 - books.google.com
At last–a new edition of the highly acclaimed book Clinical Trials in Psychiatry This book
provides a concise but thorough overview of clinical trials in psychiatry, invaluable to those …

Why do individuals agree to enrol in clinical trials? A qualitative study of health research participation in Blantyre, Malawi

J Mfutso-Bengo, P Ndebele, V Jumbe, M Mkunthi… - Malawi Medical …, 2008 - ajol.info
Current literature suggests that therapeutic misconception–a belief by participants in a
clinical trial that they are in fact simply being given clinical care–is common, especially …

Do patients with alcohol dependence respond to placebo? Results from the COMBINE Study

RD Weiss, SS O'malley, JD Hosking… - Journal of studies on …, 2008 - jsad.com
Objective: The purpose of this study was to examine the nature of the effect of placebo
medication plus accompanying medical management in the treatment of alcohol …

[图书][B] Talking cures and placebo effects

DA Jopling - 2008 - books.google.com
Psychoanalysis has had to defend itself from a barrage of criticism throughout its history.
Nevertheless, there are many who claim to have been helped by this therapy, and who claim …

[HTML][HTML] A epidemia da Aids: impacto social, científico, econômico e perspectivas

DB Greco - Estudos avançados, 2008 - SciELO Brasil
O surgimento da Aids e o aumento da incidência da infecção pelo HIV continuam como um
dos grandes desafios mundiais para o século XXI. A maneira como esse enfrentamento …