Micro (mi) RNAs are small, highly conserved noncoding RNAs that control gene expression
post-transcriptionally either via the degradation of target mRNAs or the inhibition of protein …

MicroRNAs (miRNAs) are small RNA molecules that regulate gene expression post-
transcriptionally. After the discovery of the first miRNA in the roundworm Caenorhabditis …

MicroRNA 34a (miR-34a) is a tumor suppressor gene, but how it regulates cell proliferation
is not completely understood. We now show that the microRNA miR-34a regulates silent …

The c-Myc oncogenic transcription factor (Myc) is pathologically activated in many human
malignancies. Myc is known to directly upregulate a pro-tumorigenic group of microRNAs …

Many microRNAs (miRNAs) target mRNAs involved in processes aberrant in tumorigenesis,
such as proliferation, survival, and differentiation. In particular, the let-7 miRNA family has …

Recently, we and others identified the microRNA miR-34a as a target of the tumor
suppressor gene product p53. Ectopic miR-34a induces a G1 cell cycle arrest, senescence …

Although microRNAs (miRNAs) are key regulators of gene expression in normal human
physiology and disease, transcriptional regulation of miRNAs is poorly understood, because …

Altered expression of microRNA (miRNA) is strongly implicated in cancer, and recent studies
have shown that, in cancer, expression of some miRNAs cells is silenced in association with …

MicroRNAs (miRNAs) are an abundant class of small noncoding RNAs that function as
negative gene regulators. miRNA deregulation is involved in the initiation and progression …

Abstract microRNAs in the miR-106b family are overexpressed in multiple tumor types and
are correlated with the expression of genes that regulate the cell cycle. Consistent with these …