Caveolae are specialized invaginations of the plasma membrane found in numerous cell
types. They have been implicated as playing a role in a variety of physiological processes …

Caveolae are an abundant feature of mammalian cells. Integral membrane proteins called
caveolins drive the formation of caveolae but the precise mechanisms underlying caveola …

Dysferlin and Caveolin-3 are plasma membrane proteins associated with muscular
dystrophy. Patients with mutations in the CAV3 gene show dysferlin mislocalization in …

We characterized the frequency of limb–girdle muscular dystrophy (LGMD) subtypes in a
cohort of 76 Australian muscular dystrophy patients using protein and DNA sequence …

Mutations in the caveolin-3 gene (CAV3) can lead to a broad spectrum of clinical
phenotypes. Phenotypes that have so far been associated with primary caveolin-3 …

The targeting of ion channels to cholesterol-rich membrane microdomains has emerged as
a novel mechanism of ion channel localization. Previously, we reported that Kv1. 5, a …

Caveolins are plasma-membrane-associated proteins potentially involved in a variety of
signalling pathways. Different mutations in CAV3, the gene encoding for the muscle-specific …

Mutations in or ablation of the gene encoding caveolin‐3, a protein of muscle cell caveolae,
result in forms of muscular dystrophy and cardiomyopathy. Another member of the caveolin …

Antidepressants and antipsychotics may affect several ion channels involved in the control
of cardiac action potential and be proarrhythmic. In this field, accurate understanding of …

La calpaïne 3, protéase à substrats multiples spécifique du muscle squelettique est
déficiente dans les dystrophies des ceintures de type 2A. Bien que sa (ses) fonction (s) reste …