Photoreceptor cell death mechanisms in inherited retinal degeneration
J Sancho-Pelluz, B Arango-Gonzalez… - Molecular …, 2008 - Springer
Photoreceptor cell death is the major hallmark of a group of human inherited retinal
degenerations commonly referred to as retinitis pigmentosa (RP). Although the causative …
degenerations commonly referred to as retinitis pigmentosa (RP). Although the causative …
Poly (ADP-ribose) polymerase activity in different pathologies–the link to inflammation and infarction
S Beneke - Experimental gerontology, 2008 - Elsevier
DNA repair and aging are two phenomena closely connected to each other. The poly (ADP-
ribosyl) ation reaction has been implicated in both of them. Poly (ADP-ribose) was originally …
ribosyl) ation reaction has been implicated in both of them. Poly (ADP-ribose) was originally …
Inhibitors of DNA polymerase β: Activity and mechanism
Z Gao, DJ Maloney, LM Dedkova, SM Hecht - Bioorganic & medicinal …, 2008 - Elsevier
Bioassay-guided fractionation of extracts prepared from Couepia polyandra and
Edgeworthia gardneri resulted in the isolation of the DNA polymerase β (pol β) inhibitors …
Edgeworthia gardneri resulted in the isolation of the DNA polymerase β (pol β) inhibitors …
Ethanol‐mediated DNA damage and PARP‐1 apoptotic responses in cultured fetal cortical neurons
PP Cherian, S Schenker… - Alcoholism: Clinical and …, 2008 - Wiley Online Library
Background: Prior studies by many laboratories have illustrated that ethanol can elicit a
cascade of caspase‐dependent apoptotic events in cultured neurons. Studies in our …
cascade of caspase‐dependent apoptotic events in cultured neurons. Studies in our …
Mechanisms of imporvement following functional inhibition of nitrosative stress after brun and smoke-induced acute lung injury
A Esechie - 2008 - utmb-ir.tdl.org
Severe trauma, caused by flame burn and smoke (B+ S) inhalation induces acute lung injury
(ALI) and results in the loss of pulmonary function. A cascade of molecular and cellular …
(ALI) and results in the loss of pulmonary function. A cascade of molecular and cellular …
Colorimetric Substrate and Methods for Detecting Poly (ADP-ribose) Polymerase Activity including PARP Enzymes PARP-1, VPARP, and Tankyrase-1
AC Nottbohm, RS Dothager, KS Putt… - US Patent App. 11 …, 2008 - Google Patents
Disclosed are compositions and methods capable of facilitat ing the detection and
measurement of poly (ADP-ribose) poly merases (PARP enzymes). PARP enzyme activity …
measurement of poly (ADP-ribose) poly merases (PARP enzymes). PARP enzyme activity …