In pregnancy, blood volume increases greatly and plasma osmolality is reduced, due to mild
hyponatraemia despite sodium retention. In rats, both vasopressin and oxytocin neurones in …

Systolic heart failure (HF) is a progressive disorder that often begins with asymptomatic left
ventricular (LV) systolic dysfunction and culminates in symptoms from fluid overload and …

The pathways involved in the emotional aspects of thirst, the arousal and affect associated
with the generation of thirst and the motivation to obtain satiation, have been studied but …

Circulating angiotensin II (ANGII) elicits water intake and activates the hypothalamic-pituitary-
adrenal (HPA) axis by stimulating angiotensin type 1 receptors (AT1Rs) within …

Body fluid hyperosmolality has long been known to elicit homeostatic responses that range
from drinking to inhibition of salt appetite to release of neurohypohyseal hormones (ie …

Accumulating evidence in both humans and animals indicates that acute increases in
plasma osmolality elevate sympathetic nerve activity (SNA). In addition, plasma …

Water intakes in response to hypertonic, hypovolemic, and dehydrational stimuli were
investigated in mice lacking angiotensin II as a result of deletion of the angiotensinogen …

Many mammals maintain a constant core body temperature in the face of a heat load by
using evaporative cooling responses, such as sweating, panting and spreading of saliva …

During activation of the renin-angiotensin system, hindbrain circumventricular organs such
as the area postrema have been implicated in modulating the arterial baroreflex. This study …

The neurohypophyseal hormones, arginine vasopressin and corticotropin-releasing
hormone (CRH), play a crucial role in the physiological and behavioral response to various …