Hormone and growth factor signaling in endometrial renewal: role of stem/progenitor cells

CE Gargett, RWS Chan, KE Schwab - Molecular and cellular endocrinology, 2008 - Elsevier
The human endometrium is a dynamic remodeling tissue undergoing more than 400 cycles
of regeneration, differentiation and shedding during a woman's reproductive years. The co …

Endometrial stem cells

CE Gargett - The Endometrium, 2008 - taylorfrancis.com
The endometrium of humans and some primates undergoes cyclical processes of
regeneration, differentiation, and shedding as part of the menstrual cycle. Endometrial …

[HTML][HTML] VEGF blockade inhibits angiogenesis and reepithelialization of endometrium

X Fan, S Krieg, CJ Kuo, SJ Wiegand… - The FASEB …, 2008 - ncbi.nlm.nih.gov
Despite extensive literature on vascular endothelial growth factor (VEGF) expression and
regulation by steroid hormones, the lack of clear understanding of the mechanisms of …

Inflammatory status influences aromatase and steroid receptor expression in endometriosis

O Bukulmez, DB Hardy, BR Carr, RA Word… - …, 2008 - academic.oup.com
Aberrant up-regulation of aromatase in eutopic endometrium and implants from women with
endometriosis has been reported. Aromatase induction may be mediated by increased …

Secreted frizzled-related protein 4 regulates two Wnt7a signaling pathways and inhibits proliferation in endometrial cancer cells

KS Carmon, DS Loose - Molecular cancer research, 2008 - AACR
In the endometrium, hormonal effects on epithelial cells are often elicited through stromal
hormone receptors via unknown paracrine mechanisms. Several lines of evidence support …

Mesenchymal–epithelial interactions: past, present, and future

GR Cunha - Differentiation, 2008 - Elsevier
This review summarizes the history of research on mesenchymal–epithelial interactions in
prostatic development from the first studies in 1970 to the present. From this study we have …

Innate immunity in the female reproductive tract: role of sex hormones in regulating uterine epithelial cell protection against pathogens

DO Ochiel, JV Fahey, M Ghosh… - Current women's …, 2008 - ingentaconnect.com
The mucosal immune system in the upper female reproductive tract is uniquely prepared to
maintain a balance between the presence of commensal bacteria, sexually transmitted …

[HTML][HTML] Prolonged stimulation with tumor necrosis factor-α induced partial methylation at PR-B promoter in immortalized epithelial-like endometriotic cells

Y Wu, A Starzinski-Powitz, SW Guo - Fertility and sterility, 2008 - Elsevier
The promoter of P receptor isoform B (PR-B) has recently been shown to be
hypermethylated in endometriotic tissues, but one question remains as what causes the …

Bovine endometrial stromal cells display osteogenic properties

G Donofrio, V Franceschi, A Capocefalo… - Reproductive Biology …, 2008 - Springer
The endometrium is central to mammalian fertility. The endometrial stromal cells are very
dynamic, growing and differentiating throughout the estrous cycle and pregnancy. In …

[HTML][HTML] The knockdown of progesterone receptor isoform B (PR-B) promotes proliferation in immortalized endometrial stromal cells

Y Wu, X Shi, SW Guo - Fertility and sterility, 2008 - Elsevier
The knockdown of PR-B by siRNA resulted in a significant increase in proliferation in an
immortalized endometrial stromal cell line. This suggests that PR-B knockdown might be …