Nanotechnology is a field of research at the crossroads of biology, chemistry, physics,
engineering, and medicine. Design of multifunctional nanoparticles capable of targeting …

Background: Liposomes, phospholipids, nanosized bubbles with a bilayered membrane
structure, have drawn a lot of interest as pharmaceutical carriers for drugs and genes. In …

Integrin ανβ3 is found on a subset of tumor blood vessels where it is associated with
angiogenesis and malignant tumor growth. We designed an ανβ3-targeted nanoparticle …

Epidermal growth factor receptor (EGFR) is an important anti-cancer therapy target that is
applicable to many cancer types. We had previously reported the screening and discovery of …

Targeting the tumor vasculature and selectively modifying endothelial functions is an
attractive anti-tumor strategy. We prepared polyethyleneglycol modified immunoliposomes …

Doxorubicin remains the first line of treatment for various cancers ever since its discovery in
1971. Cardiotoxicity and nephrotoxicity associated with unformulated doxorubicin triggered …

Adhesion is a hallmark of haematological and solid cancer cells. All five classes of cell
adhesion molecules (CAM)-integrins, cadherins, immunoglobulin-like CAMs, selectins and …

The use of nanoparticulate pharmaceutical carriers to enhance the in vivo efficiency of many
drugs and drug administration protocols well established itself over the past decade both in …

In this study, a new poly (lactic acid)–poly (ethylene oxide)‐Arg‐Gly‐Asp (PLA‐PEO‐RGD)
derivative was synthesized, and paclitaxel‐loaded PLA‐PEO‐RGD micelles were prepared …

Focal cerebral ischemia, known as stroke, is caused by a sudden interruption in the blood
supply to the brain. We attempted to identify peptides that can home to ischemic stroke …