Early phase pharmacokinetics but not pharmacodynamics are influenced by propofol infusion rate
K Masui, M Kira, T Kazama, S Hagihira… - The Journal of the …, 2009 - pubs.asahq.org
Background Conventional compartmental pharmacokinetic models wrongly assume
instantaneous drug mixing in the central compartment, resulting in a flawed prediction of …
instantaneous drug mixing in the central compartment, resulting in a flawed prediction of …
Comparison of the sedative properties of CNS 7056, midazolam, and propofol in sheep
Background CNS 7056 is an esterase-metabolized benzodiazepine sedative currently
under development. Its short duration of action would suggest a clinical role similar to …
under development. Its short duration of action would suggest a clinical role similar to …
[HTML][HTML] Translational pain research: Evaluating analgesic effect in experimental visceral pain models
AE Olesen, T Andresen, LL Christrup… - World journal of …, 2009 - ncbi.nlm.nih.gov
Deep visceral pain is frequent and presents major challenges in pain management, since its
pathophysiology is still poorly understood. One way to optimize treatment of visceral pain is …
pathophysiology is still poorly understood. One way to optimize treatment of visceral pain is …
[图书][B] Pharmacokinetics of propofol in cats
L Bester - 2009 - search.proquest.com
Since the introduction of the lipid emulsion formulation in 1986, propofol has become
established for induction as well as for maintenance of anaesthesia in veterinary practice1 …
established for induction as well as for maintenance of anaesthesia in veterinary practice1 …
[图书][B] The Analgesic Profiles of Opioids in Human Experimental Pain Models
AE Olesen - 2009 - vbn.aau.dk
Chronic pain of moderate to severe intensity occurs in 19% of adult Europeans, seriously
affecting the quality of their social and working lives. Very few are managed by pain …
affecting the quality of their social and working lives. Very few are managed by pain …