Many cancer immunotherapies developed in experimental animals have been tested in
clinical trials. Although some have shown modest clinical effects, most have not been …

Purpose: Immune dysfunction reported in renal cell carcinoma (RCC) patients may
contribute to tumor progression. Myeloid-derived suppressor cells (MDSC) represent one …

Several immune suppressive mechanisms that evade the host immune response have been
described in patients with hepatocellular carcinoma (HCC); one of these mechanisms is …

Over the last years a number of reports have described elevated numbers of regulatory T
(Treg) cells inside of tumors, in close proximity of the tumor, draining lymph nodes and also …

Myeloid-derived suppressor cells (MDSC) contribute to immune dysfunctions induced by
tumors both in experimental models and patients. In mice, MDSC are phenotypically …

Immunosuppression mediated by regulatory T cells (Tregs) is a key facilitator of tumor
immune evasion, but the source of these Tregs and their contribution to human cancer …

Tumor-induced immunosuppression plays a key role in tumor evasion of the immune
system. A key cell population recognized as myeloid-derived suppressor cells (MDSC) …

Обзор представляет анализ данных литературы о роли ряда клеток системы
иммунитета (макрофаги, нейтрофилы, тучные клетки, эозинофилы), выделяемых ими …

Immunotherapy and angiogenic inhibitors, used alone or in combination with chemotherapy,
represent two promising cancer treatment programs. Each is limited by myeloid-derived …

Background At the early stages of carcinogenesis, the induction of tumor specific T cell
mediated immunity seems to block the tumor growth and give protective anti-tumor immune …