Background Older women with breast cancer are underrepresented in clinical trials, and
data on the effects of adjuvant chemotherapy in such patients are scant. We tested for the …

The comprehensive geriatric assessment (CGA), originally developed by geriatricians as a
multidimensional evaluation of the older patients, has become in the recent years a …

With a median age at diagnosis of 71 years old and the aging of the US population, colon
cancer commonly occurs in the elderly. Adjuvant chemotherapy has been standard of care …

Purpose There is no standard treatment for patients with advanced urothelial cancer who
are ineligible (“unfit”) for cisplatin-based chemotherapy (CHT). To compare the activity and …

BACKGROUND: Trial accrual patterns were examined to determine whether metastatic
colorectal cancer (mCRC) patients enrolled in trials are representative of a general cancer …

Background Providing cancer patients with adequate treatment information is important for
patients' health, well-being and satisfaction. Nurses play an important role in patient …

BACKGROUND. Adequate representation of women in research has been deemed
essential. METHODS. Cancer research published in 8 journals in 2006 was reviewed. The …

Purpose Although, for patients with cancer, comorbidity can affect the timing of cancer
detection, treatment, and prognosis, there is little information relating to the question of …

BACKGROUND: The purpose of this study was to determine the risk of chemotherapy‐
associated cardiac toxicity, including cardiac dysrhythmia, cardiomyopathy, congestive heart …

BACKGROUND: Irinotecan‐based chemotherapy regimens are 1 option for treatment of
metastatic colorectal cancer (mCRC). The authors report the safety and efficacy of such …