MG53 nucleates assembly of cell membrane repair machinery
Dynamic membrane repair is essential not only for long-term maintenance of cellular
integrity but also for recovery from acute cell injury. While compromised membrane repair …
integrity but also for recovery from acute cell injury. While compromised membrane repair …
An evolutionary history of P2X receptors
SJ Fountain, G Burnstock - Purinergic signalling, 2009 - Springer
Adenosine triphosphate (ATP) is an ancient and fundamentally important biological
molecule involved in both intracellular and extracellular activities. P2X ionotropic and P2Y …
molecule involved in both intracellular and extracellular activities. P2X ionotropic and P2Y …
Minor sarcoplasmic reticulum membrane components that modulate excitation–contraction coupling in striated muscles
S Treves, M Vukcevic, M Maj… - The Journal of …, 2009 - Wiley Online Library
In striated muscle, activation of contraction is initiated by membrane depolarisation caused
by an action potential, which triggers the release of Ca2+ stored in the sarcoplasmic …
by an action potential, which triggers the release of Ca2+ stored in the sarcoplasmic …
[HTML][HTML] Tetrameric Orai1 is a teardrop-shaped molecule with a long, tapered cytoplasmic domain
The Ca 2+ release-activated Ca 2+ channel is a principal regulator of intracellular Ca 2+
rise, which conducts various biological functions, including immune responses. This …
rise, which conducts various biological functions, including immune responses. This …
Essential role of the TRIC-B channel in Ca2+ handling of alveolar epithelial cells and in perinatal lung maturation
D Yamazaki, S Komazaki, H Nakanishi, A Mishima… - 2009 - journals.biologists.com
TRIC channels function as monovalent cation-specific channels that mediate counter ion
movements coupled with ryanodine receptor-mediated Ca2+ release from intracellular …
movements coupled with ryanodine receptor-mediated Ca2+ release from intracellular …
New molecular components supporting ryanodine receptor-mediated Ca2+ release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes
D Yamazaki, T Yamazaki, H Takeshima - Pharmacology & therapeutics, 2009 - Elsevier
Ca2+ mobilization from intracellular stores is mediated by Ca2+ release channels,
designated ryanodine and IP3 receptors, and directly regulates important cellular reactions …
designated ryanodine and IP3 receptors, and directly regulates important cellular reactions …
[HTML][HTML] Reconstruction of the P2X2 receptor reveals a vase-shaped structure with lateral tunnels above the membrane
In response to the intercellular messenger ATP, P2X receptors transfer various sensory
information, including pain. Here we have reconstructed the structure of the P2X 2 receptor …
information, including pain. Here we have reconstructed the structure of the P2X 2 receptor …
[HTML][HTML] Ca2+ transport and heat production in vesicles derived from the sarcoplasmic reticulum terminal cisternae: Regulation by K+
In this work, we compared the effect of K+ on vesicles derived from the longitudinal (LSR)
and terminal cisternae (HSR) of rabbit white muscle. In HSR, K+ was found to inhibit both the …
and terminal cisternae (HSR) of rabbit white muscle. In HSR, K+ was found to inhibit both the …
ER localized bestrophin1 activates Ca2+ dependent ion channels TMEM16A and SK4
R Barro-Soria, F AlDehni, J Almaça, J Ousingsawat… - Nature …, 2009 - nature.com
Abstract Bestrophins form Ca2+ activated Cl-channels and regulate intercellular Ca2+
signaling1. We demonstrate that bestrophin 1 is localized in the endoplasmic reticulum (ER) …
signaling1. We demonstrate that bestrophin 1 is localized in the endoplasmic reticulum (ER) …