Harnessing invariant NKT cells in vaccination strategies

V Cerundolo, JD Silk, SH Masri, M Salio - Nature Reviews Immunology, 2009 - nature.com
To optimize vaccination strategies, it is important to use protocols that can'jump-start'immune
responses by harnessing cells of the innate immune system to assist the expansion of …

Natural killer T cells and autoimmune disease

L Wu, LV Kaer - Current molecular medicine, 2009 - ingentaconnect.com
Natural killer T (NKT) cells are an unusual subset of innate immune cells that express a
surface receptor generated by somatic DNA rearrangement, a hallmark of cells of the …

Invariant NKT cells and CD1d+ cells amass in human omentum and are depleted in patients with cancer and obesity

L Lynch, D O'Shea, DC Winter… - European journal of …, 2009 - Wiley Online Library
Invariant NKT (iNKT) cells recognize lipid antigens presented by CD1d and respond rapidly
by killing tumor cells and release cytokines that activate and regulate adaptive immune …

Combination therapy of in vitro‐expanded natural killer T cells and α‐galactosylceramide‐pulsed antigen‐presenting cells in patients with recurrent head and neck …

N Kunii, S Horiguchi, S Motohashi… - Cancer …, 2009 - Wiley Online Library
The aim of this clinical trial was to investigate the feasibility of intra‐arterial infusion of in vitro‐
expanded Vα24 natural killer T (NKT) cells combined with submucosal injection of α …

Enrichment of human CD4+ Vα24/Vβ11 invariant NKT cells in intrahepatic malignant tumors

G Bricard, V Cesson, E Devevre… - The Journal of …, 2009 - journals.aai.org
Invariant NKT cells (iNKT cells) recognize glycolipid Ags via an invariant TCR α-chain and
play a central role in various immune responses. Although human CD4+ and CD4− iNKT …

MHC class II‐expressing thymocytes suppress invariant NKT cell development

W Li, MH Sofi, DG Wei, W Du… - Immunology and cell …, 2009 - Wiley Online Library
Natural killer T (NKT) cells are positively selected on cortical thymocytes expressing the non‐
classical major histocompatibility complex (MHC) class I CD1d molecules. However, it is …

B cell helper assays

S Abrignani, E Tonti, G Casorati… - T Cell Protocols: Second …, 2009 - Springer
Activation, proliferation and differentiation of naïve B lymphocytes into memory B cells and
plasma cells requires engagement of the B cell receptor (BCR) coupled to T-cell help (1, 2) …

[图书][B] The differential requirement for vitamin D and vitamin D receptor in iNKT cell development

S Yu - 2009 - search.proquest.com
CD1d-reactive natural killer T (NKT) cells with an invariant T cell receptor Vα14
rearrangement are a unique subset of lymphocytes, which play important roles in immune …